Rchr
J-GLOBAL ID:201401025470837480   Update date: Apr. 21, 2021

Okuda Hiroshi

Okuda Hiroshi
Affiliation and department:
Research field  (1): Tumor biology
Research theme for competitive and other funds  (6):
  • 2020 - 2023 がん遺伝子MLL-AF4のRNA結合因子による発がん抑制機構
  • 2016 - 2020 新規MLL-AEP転写活性化複合体を介した白血病化メカニズム
  • 2017 - 2019 Mechanism of leukemogenesis through MLL-AF4 and its regulatory factors
  • 2013 - 2015 Mechanisms of niche-independent self-renewal by MLL fusion proteins
  • 2013 - 2015 Mechanism of transcriptional activation and leukemogenesis by AF4
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Papers (28):
  • Akiko Nagamachi, Akinori Kanai, Megumi Nakamura, Hiroshi Okuda, Akihiko Yokoyama, Satoru Shinriki, Hirotaka Matsui, Toshiya Inaba. Multi-organ failure with abnormal receptor metabolism in mice mimicking Samd9/9L syndromes. The Journal of clinical investigation. 2020
  • Ryo Miyamoto, Hiroshi Okuda, Akinori Kanai, Satoshi Takahashi, Takeshi Kawamura, Hirotaka Matsui, Toshio Kitamura, Issay Kitabayashi, Toshiya Inaba, Akihiko Yokoyama. Activation of CpG-Rich Promoters Mediated by MLL Drives MOZ-Rearranged Leukemia. Cell reports. 2020. 32. 13. 108200-108200
  • Hiroshi Okuda, Akihiko Yokoyama. Myeloid Progenitor Transformation Assay. BIO-PROTOCOL. 2017. 7. 23
  • Hiroshi Okuda, Akihiko Yokoyama. In vivo Leukemogenesis Model Using Retrovirus Transduction. BIO-PROTOCOL. 2017. 7. 23
  • Hiroshi Okuda, Boban Stanojevic, Akinori Kanai, Takeshi Kawamura, Satoshi Takahashi, Hirotaka Matsui, Akifumi Takaori-Kondo, Akihiko Yokoyama. Cooperative gene activation by AF4 and DOT1L drives MLL-rearranged leukemia. The Journal of clinical investigation. 2017. 127. 5. 1918-1931
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Education (3):
  • 2004 - 2007 Kindai University Major in Advanced life Science
  • 2002 - 2004 Kindai University Major in Advanced life Science
  • 1998 - 2002 Kindai University
Professional career (1):
  • 博士(農学) (近畿大学)
Work history (6):
  • 2021/04 - 現在 Yokohama City University
  • 2017/04 - 2021/03 National Cancer Center
  • 2014/04 - 2016/03 Kyoto University Graduate School of Medicine
  • 2012/01 - 2014/03 Kyoto University Graduate School of Medicine
  • 2008/04 - 2011/11 Southern Illinois University School of Medicine Postdoctoral fellow
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Association Membership(s) (3):
日本分子生物学会 ,  日本血液学会 ,  日本癌学会
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