Rchr
J-GLOBAL ID：201401025871403008
Update date: Dec. 13, 2024
Kuwabara Takashige
クワバラ タカシゲ | Kuwabara Takashige
Affiliation and department：
Job title：
Associate Professor
Research field (1)：
Nephrology
Research theme for competitive and other funds (13)：
- 2022 - 2025 Elucidation of the role of TRPV4 channel in the effect of repetitive hyperthermia on the progression of chronic kidney disease
- 2022 - 2025 Role of MRP8 in the mechanism of acute kidney injury through cell-mediated immunity
- 2021 - 2024 腎に発現するTRPチャネルの温熱プレコンディショニングに対する役割
- 2019 - 2022 Role of MRP8 in the progression of glomerulonephritis
- 2018 - 2022 Elucidation of the mechanism of cisplatin-induced nephropathy reduction by thermal preconditioning
- 2018 - 2021 The effects of systemic thermal habits on chronic kidney disease onset and progression and their underlying mechanisms elucidation
- 2017 - 2020 Elucidation of the role of homeostatic inflammation in the AKI to CKD transition mechanism focusing on the time phase changes
- 2017 - 2019 Elucidation of the role of MRP8 through inflammation and ER stress in metabolic syndrome related nephropathy
- 2015 - 2018 Suppressive effects of mild sauna stimulation on chronic kidney disease progression
- 2015 - 2018 The role of MRP8 as a therapeutic target in chronic kidney disease
- 2014 - 2017 Roles of humoral factors and organ-organ or cell-cell communications in the development and progression of metabolic kidney diseases
- 2013 - 2015 The relationship between homeostatic inflammation and renin-angiotensin system in the progression of diabetic nephropathy
- 2011 - 2012 Novel mechanism of progression of diabetic nephropathy by hyperlipidemia: MRP8/TLR4 signaling
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Papers (331)：
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Ryosuke Yamamura, Yu Nagayoshi, Kayo Nishiguchi, Hitomi Kaneko, Keiichi Yamamoto, Koki Matsushita, Miho Shimamura, Akihiro Kunisawa, Korin Sakakida, Takeshi Chujo, et al. Bacteria-specific modified nucleoside is released and elevated in urine of patients with bacterial infections. mBio. 2024
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Makoto Ono, Yuichiro Izumi, Kosuke Maruyama, Yukiko Yasuoka, Akiko Hiramatsu, Jose Aramburu, Cristina López-Rodríguez, Hiroshi Nonoguchi, Yutaka Kakizoe, Masataka Adachi, et al. Characterization of gene expression in the kidney of renal tubular cell-specific NFAT5 knockout mice. American journal of physiology. Renal physiology. 2023
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Yoshikazu Miyasato, Jun Morinaga, Hideki Inoue, Yushi Nakayama, Masataka Adachi, Yuichiro Izumi, Yutaka Kakizoe, Teruhiko Mizumoto, Terumasa Nakagawa, Daisuke Fujimoto, et al. Association between prognostic nutritional index and peritoneal dialysis discontinuation: a retrospective cohort study. Renal Replacement Therapy. 2023. 9. 1
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Yasunobu Iwata, Qinyuan Deng, Yutaka Kakizoe, Terumasa Nakagawa, Yoshikazu Miyasato, Miyuki Nakagawa, Kayo Nishiguchi, Yu Nagayoshi, Yuki Narita, Yuichiro Izumi, et al. A Serine Protease Inhibitor, Camostat Mesilate, Suppresses Urinary Plasmin Activity and Alleviates Hypertension and Podocyte Injury in Dahl Salt-Sensitive Rats. International journal of molecular sciences. 2023. 24. 21
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矢野 祐子, 神吉 智子, 上村 直道, 秦 雄介, 藤本 大介, 水本 輝彦, 泉 裕一郎, 桑原 孝成, 安達 政隆, 向山 政志. COVID-19を契機に急性間質性腎炎を発症した1例. 日本腎臓学会誌. 2023. 65. 6-W. 782-782
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MISC (153)：
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道脇なつみ, 鵜木隼平, 小山直子, 下河優奈, 桑原孝成, 向山政志, 成田勇樹, 成田勇樹, 城野博史, 城野博史, et al. 虚血性急性腎障害併発糖尿病モデルラットの腎病態進展におけるインドキシル硫酸の役割解明. 日本医療薬学会年会講演要旨集(Web). 2021. 31
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桑原孝成, 向山政志. Immunotherapies-associated kidney adverse effects. 日本腎臓学会誌(Web). 2021. 63. 3
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道脇なつみ, 鵜木隼平, 小山直子, 下河優奈, 桑原孝成, 向山政志, 成田勇樹, 城野博史, 齋藤秀之. 糖尿病虚血性急性腎障害併発モデルラットの病態進展におけるインドキシル硫酸の関与. 日本腎臓学会誌(Web). 2020. 62. 4
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吉積麻美, 實吉拓, 松下恭久, 松永愛子, 桑原孝成, 井上秀樹, 安達政隆, 澤田貴彰, 中村公俊, 向山政志. 弟の腎生検をきっかけにヘテロ接合体Fabry病と診断できた一例. 日本腎臓学会誌(Web). 2020. 62. 6
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桑原孝成, 向山政志. 糖尿病性腎臓病における自然炎症と細胞連関. 日本内分泌学会雑誌. 2020. 96. 1
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Work history (3)：
- 2021/01 - 現在 Kumamoto University Faculty of Life Sciences
- 2017 - Kumamoto University Faculty of Life Sciences
- 2015 - Assistant Professor,Faculty of Life Sciences(Clinical medicine group),Kumamoto University
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