Hirai Yuya

Affiliation and department：

Research field (1)： Cell biology

Research theme for competitive and other funds (5)：

2024 - 2027 Mechanism of mononegavirus nucleocapsid formation
2023 - 2026 Elucidation of structure-function relationships of nuclear viral inclusion bodies formed by liquid-liquid phase separation
2019 - 2021 Elucidation of the mechanism by which RNA helicases regulate the functional relationship between nucleoli and stress granules.
2014 - 2017 The elucidation of the localization mechanism of RNP to the mitotic chromosomes by using the virus
2009 - 2011 動的核マトリクスの構造及び動態の解析

Papers (17)：

Yuya Hirai, Yoshimasa Makita, Makoto Nakagawa, Rie Kakehashi, Shin-Ichi Fujiwara. Cytosolic protein delivery via protein-bound microparticles based on anionic boron clusters and cationic polymers. Biomaterials science. 2025
Yuya Hirai, Yoshimasa Makita, Jun Asaoka, Yuka Aoyagi, Akihiro Nomoto, Hideyuki Okamura, Shin-Ichi Fujiwara. Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes. ACS omega. 2023. 8. 38. 35321-35327
Yuya Hirai, Masayuki Horie. Nyamanini Virus Nucleoprotein and Phosphoprotein Organize Viral Inclusion Bodies That Associate with Host Biomolecular Condensates in the Nucleus. International Journal of Molecular Sciences. 2023. 24. 7. 6550-6550
Yuya Hirai, Keizo Tomonaga, Masayuki Horie. Borna disease virus phosphoprotein triggers the organization of viral inclusion bodies by liquid-liquid phase separation. International journal of biological macromolecules. 2021. 192. 55-63
Yuya Hirai, Keizo Tomonaga, Masayuki Horie. The mechanism underlying the organization of Borna disease virus inclusion bodies is unique among mononegaviruses. 2021

ｍore...

MISC (1)：

Masahiro Kumeta, Yasuhiro Hirano, Yuya Hirai, Ken Hashida, Shige H. Yoshimura, Kunio Takeyasu. Mitotic specific translocation of one of the focal adhesion proteins, α-actinin 4, to the nucleolar organizer regions. EMBO workshop: The nucleolus and disease. 2008

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