Rchr
J-GLOBAL ID：201401038475812277   Update date: Jan. 30, 2024

Koga Motokazu

コガ モトカズ | Koga Motokazu
Research field  (2)： Pharmacology ,  Anesthesiology
Research keywords  (3)： anesthesiology ,  pulmonary hypertrnsion ,  GPR143
Research theme for competitive and other funds  (7)：
  • 2020 - 2023 Protein kinase Dの肺高血圧症への関与解明と核酸医薬による制御
  • 2019 - 2023 重症肺高血圧モデルラットを用いた肺動脈コンプライアンスの検討および治療戦略の確立
  • 2017 - 2022 Exosome of mesenchymal stem cells for the treatment of pulmonary hypertension with microRNA.
  • 2017 - 2022 Role of protein kinase D in vasoconstriction
  • 2018 - 2021 Dopa as a neurotransmitter in heart failure and acute kidney injury
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Papers (13)：
  • Masayuki Nakano, Motokazu Koga, Tatsuo Hashimoto, Natsuki Matsushita, Daiki Masukawa, Yusuke Mizuno, Hiraku Uchimura, Ryo Niikura, Tomoyuki Miyazaki, Fumio Nakamura, et al. Right ventricular overloading is attenuated in monocrotaline-induced pulmonary hypertension model rats with a disrupted Gpr143 gene, the gene that encodes the 3,4-l-dihydroxyphenyalanine (l-DOPA) receptor. Journal of pharmacological sciences. 2022. 148. 2. 214-220
  • Yuka Kasahara, Daiki Masukawa, Yoshie Nakamura, Koshi Murata, Tatsuo Hashimoto, Kohtaro Takizawa, Motokazu Koga, Fumio Nakamura, Yugo Fukazawa, Kengo Funakoshi, et al. Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions. Neuroscience Research. 2021. 170. 370-375
  • Chisaki Yokoyama, Takahiro Mihara, Shizuka Kashiwagi, Motokazu Koga, Takahisa Goto. Effects of intravenous dextrose on preventing postoperative nausea and vomiting: A systematic review and meta-analysis with trial sequential analysis. PloS one. 2020. 15. 4. e0231958
  • Goshima Y, Watanabe S, Seki E, Koga M, Masukawa D, Nakamura F, Komori T, Arai N. Immunoreactivity of a G protein-coupled l-DOPA receptor GPR143, in Lewy bodies. Neuroscience research. 2018
  • Masukawa D, Koga M, Sezaki A, Nakao Y, Kamikubo Y, Hashimoto T, Okuyama-Oki Y, Aladeokin AC, Nakamura F, Yokoyama U, et al. L-DOPA sensitizes vasomotor tone by modulating the vascular alpha1-adrenergic receptor. JCI insight. 2017. 2. 18
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MISC (14)：
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Lectures and oral presentations  (5)：
  • 全身麻酔時のアンダーブランケットを用いた早期加温開始による患者体温低下予防効果の検討
    (日本手術医学会誌 2014)
  • 薬剤溶出性ステント留置後8ヵ月後の手術によりステント内血栓症を発症した症例
    (循環制御 2008)
  • In vitroにおけるHAP1(huntingtin-associated protein1)とポリグルタミン蛋白の相互作用について
    (解剖学雑誌 2003)
  • DNAチップを用いた内分泌かく乱化学物質の精巣構成細胞への影響解析
    (日本薬学会年会要旨集 2002)
  • 内分泌攪乱物質のセルトリ細胞機能に及ぼす影響 アッセイ系の確立
    (環境ホルモン学会研究発表会要旨集 2000)
Professional career (2)：
  • 博士(医学) (横浜市立大学)
  • 修士(薬学) (東京理科大学)
Work history (5)：
  • 2021/04 - 現在 Yokohama City University School of Medicine
  • 2021/04 - 現在 Kanagawa Cancer Center Department of Anesthesiology
  • 2019/04 - 2021/03 Yokohama City University School of Medicine Department of Anesthesiology Assistant Professor
  • 2018/04 - 2019/03 Yokohama City University Hospital Department of Anesthesiology Assistant Professor
  • 2014/04 - 2018/03 Yokohama City University Academic Association of Medical Science Department of Molecularpharmacology and Neurobiology Assistant Professor
Association Membership(s) (6)：
American Society of Anesthesiologists ,  European Society of Anaesthesiology ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  JAPANESE ASSOCIATION FOR OPERATIVE MEDICINE ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  JAPANESE SOCIETY OF ANESTHESIOLOGISTS
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