Develasco Marco

デベラスコマルコ | Develasco Marco

Affiliation and department：
Homepage URL (2)： http://kaken.nii.ac.jp/d/r/20449838.ja.html , https://kaken.nii.ac.jp/en/search/?qm=20449838

Research field (5)： Tumor biology , Molecular biology , Tumor diagnostics and therapeutics , Urology , Immunology

Research keywords (20)： Personalized therapy , Urological cancers , Tumor biology , Biomarker discovery , Immunotherapy , Molecular Targeting , Prostate cancer , Preclincal models , Preclinical Testing , 前立腺癌 , 動物モデル , ノックアウトマウス , ペプチド , 腎細胞癌 , 分子標的治療 , ペプチドワクチン , ワクチン療法 , 免疫療法 , 腫瘍 , 尿路上皮癌

Research theme for competitive and other funds (16)：

2023 - 2026 Validation study of a model for estimating the primary organ of cancer of unknown primary by methylation analysis of circulating tumor DNA
2023 - 2026 腸内細菌叢によるアンドロゲンシグナル経路を介した去勢抵抗性前立腺癌進展機序の解明
2023 - 2026 Validation study of a model to estimate the primary organ of cancer of unknown primary
2022 - 2025 腎細胞がんに対する癌ワクチンを用いた複合免疫療法の有用性に関する検討
2020 - 2023 Establishment of aminoacid transporter directed prostate cancer therapy based on the liquid biopsy

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Papers (233)：

Chisato Wakamori, Marco A. De Velasco, Kazuko Sakai, Yurie Kura, Makoto Matsushita, Saizo Fujimoto, Koji Hatano, Norio Nonomura, Kazutoshi Fujita, Kazuto Nishio, et al. A cross-species analysis of fecal microbiomes in humans and mice reveals similarities and dissimilarities associated with prostate cancer risk. The Prostate. 2024
Marco A. De Velasco, Kazuko Sakai, Seiichiro Mitani, Yurie Kura, Shuji Minamoto, Takahiro Haeno, Hidetoshi Hayashi, Kazuto Nishio. A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin. International Journal of Clinical Oncology. 2024
Yurie Kura, Marco A De Velasco, Kazuko Sakai, Hirotsugu Uemura, Kazutoshi Fujita, Kazuto Nishio. Exploring the relationship between ulcerative colitis, colorectal cancer, and prostate cancer. Human cell. 2024
Marco Antonio De Velasco. Moving toward improved immune checkpoint immunotherapy for advanced prostate cancer. International Journal of Urology. 2024
Terufumi Yoshida, Kazuko Sakai, Masaki Kaibori, Mitsuaki Ishida, Shogo Tanaka, Shoji Kubo, Takuya Nakai, Marco De Velasco, Hideyuki Matsushima, Koji Tsuta, et al. Downregulated expression of PBRM1 in sarcomatoid hepatocellular carcinoma. Oncology Letters. 2024. 27. 3

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MISC (215)：

若森千怜, デベラスコ・マルコ, 倉由吏恵, 藤田和利, 坂井和子, 松下慎, 森康範, 野澤昌弘, 西本光寿, 吉村一宏, et al. ヒトおよびマウスの前立腺癌腸内細菌叢の包括的解析について(Integrative gut microbiome analysis of human and mouse prostate cancer). 日本癌学会総会記事. 2023. 82回. 71-71
植村天受, 倉由吏恵, 藤田和利, 坂井和子, シュラー・アルウイン, サッハセンマイヤー・クリス, 野澤昌弘, 吉村一宏, 西尾和人, デベラスコ・マルコ. 前立腺癌マウスにおける腫瘍浸潤ミエロイド細胞について(Targeting tumor immunosuppressive myeloid cells in mouse Pten-null prostate cancer). 日本癌学会総会記事. 2023. 82回. 408-408
デベラスコ・マルコ, 倉由吏恵, 藤田和利, 西本光寿, 坂井和子, 吉村一宏, 野澤昌弘, ハモンド・スコット, ドベディ・シモン, デービス・バリー, et al. 前臨床癌マウスモデルにおけるPD-L1に対する抗薬物抗体の制御について(Preclinical model to counter antidrug antibodies to programmed cell death-1 blockade). 日本癌学会総会記事. 2023. 82回. 1019-1019
デベラスコ・マルコ, 倉由吏恵, 坂井和子, 藤田和利, 橋本士, 坂野恵里, 西本光寿, 野澤昌弘, 吉村一宏, 西尾和人, et al. 前立腺癌Ptenノックアウトマウスを用いたCD73とA2aR阻害の効果について(Efficacy of combined CD73 and A2aR blockade in mouse Pten-deficient prostate cancer). 日本泌尿器科学会総会. 2023. 110回. OP76-02
植村天受, 倉由吏恵, 藤田和利, 坂井和子, 橋本士, 西本光寿, 吉村一宏, 野澤昌弘, 西尾和人, デベラスコ・マルコ. アンドロゲン受容体シグナル阻害を標的とした分子および免疫応答を評価可能とする前臨床前立腺癌マウスモデルの活用について(Use of a preclinical prostate cancer model to assess molecular and immune responses to androgen receptor signaling axis blockade). 日本泌尿器科学会総会. 2023. 110回. OP76-03

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Lectures and oral presentations (134)：

Abstract 2877: Profiling of myeloid-derived suppressor cells in Pten-deficient in prostate cancer progression
(American Association for Cancer Research Annual Meeting 2023 2023)
Abstract 622: Gene panel-based immune profiling of human cancers
(Cancer Research 2021)
Abstract 1780: Associations between gut microbiota and PD-L1 immunotherapy/JAK1/2 inhibition in mousePten-deficient prostate cancer
(Cancer Research 2021)
Abstract 1438: Acute immune responses to apalutamide in mousePten-deficient prostate cancer
(Cancer Research 2021)
Abstract 1568: A2aR inhibition enhances the antitumor activity of CTLA4 blockade in mouse Pten-deficient prostate cancer
(Cancer Research 2021)

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Professional career (1)：

Ph.D. (Kindai University)

Work history (2)：

2023/04 - 現在 Kindai University Faculty of Medicine Department of Gemone Biology Lecturer
2006 - 2022/03 Kindai University Faculty of Medicine Genome Biology

Association Membership(s) (3)：

THE JAPANESE UROLOGICAL ASSOCIATION , THE JAPANESE CANCER ASSOCIATION , American Association for Cancer Research

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