Tago Kenji

タゴケンジ | Tago Kenji

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/20306111.ja.html

Research field (1)： Functional biochemistry

Research keywords (20)：シグナル伝達 , 細胞情報伝達機構 , 癌 , シグナル伝達系 , がん , 蛋白質 , 細胞・組織 , 薬理学 , 受容体 , 生体分子 , Gタンパク質 , Gタンパク質共役受容体 , 新規分子プローブ , G蛋白質共役受容体 , 細胞遊走制御 , G蛋白質 , 創薬科学 , 機能抗体 , オーファン受容体 , モノクローナル抗体

Research theme for competitive and other funds (10)：

2022 - 2025 アティピカルRasファミリーが制御する発がん抑制シグナルの解析
2017 - 2020 Analysis of nuclear signaling complexes of novel Ras family and their activities to induce cellular transformation
2014 - 2017 Analysis of oncogenic signals regulated by novel type of Ras family protein
2014 - 2017 Investigation on inhibitory mechanism of soluble ST2 protein (secreted IL-33 receptor) against LPS signal
2013 - 2016 Study on the mechanism of cell growth regulation by ST2 and its possible anti-cancerous effect.

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Papers (109)：

Kengo Takeda, Satoshi Ohta, Miu Nagao, Erika Kobayashi, Kenji Tago, Megumi Funakoshi-Tago. FL118 Is a Potent Therapeutic Agent against Chronic Myeloid Leukemia Resistant to BCR-ABL Inhibitors through Targeting RNA Helicase DDX5. International journal of molecular sciences. 2024. 25. 7
Akira Korai, Xin Lin, Kenji Tago, Megumi Funakoshi-Tago. The acetylation of STAT3 at K685 attenuates NPM-ALK-induced tumorigenesis. Cellular signalling. 2024. 114. 110985-110985
Taisuke Murata, Kenji Tago, Kota Miyata, Yasuhiro Moriwaki, Hidemi Misawa, Kenji Kobata, Yosuke Nakazawa, Hiroomi Tamura, Megumi Funakoshi-Tago. Suppression of Neuroinflammation by Coffee Component Pyrocatechol via Inhibition of NF-κB in Microglia. International journal of molecular sciences. 2023. 25. 1
Taisuke Murata, Sho Ishiwa, Xin Lin, Yosuke Nakazawa, Kenji Tago, Megumi Funakoshi-Tago. The citrus flavonoid, nobiletin inhibits neuronal inflammation by preventing the activation of NF-κB. Neurochemistry international. 2023. 171. 105613-105613
Shingo Hokimoto, Megumi Funakoshi-Tago, Kenji Tago. Identification of DDX5 as an indispensable activator of the glucocorticoid receptor in adipocyte differentiation. The FEBS journal. 2023. 290. 4. 988-1007

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MISC (90)：

多胡憲治. Immunoblotting法の基礎と応用. 組織細胞化学. 2023. 2023
向來朗, リン・シン, 多胡めぐみ, 多胡憲治. 融合型チロシンキナーゼNPM-ALKによる発がん誘導におけるSTAT3のアセチル化の機能解析. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-02
武田健吾, 多胡憲治, 上田史仁, 多胡めぐみ. エリスロポエチンによるSTAT5非依存的な細胞増殖誘導の分子機構の解析. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-04
多胡憲治, 杉山直幸, 太田聡, 大村千尋, 松儀実広, 柳澤健, 冨永薫, 伊東広, 多胡めぐみ. κB-Ras結合タンパク質TRB3は新規のがん抑制シグナル分子として機能する. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-05
大多和宏季, 大村千尋, 太田聡, 松儀実広, 多胡めぐみ, 富永薫, 多胡憲治. Ras発がんシグナルにおける新規がん抑制遺伝子産物RGS16の機能解析. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 2T12a-08

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Education (2)：

1993 - 1998 Tokyo Institute of Technology
1989 - 1993 Saitama University

Professional career (1)：

博士(理学) (東京工業大学)

Work history (5)：

2023/04 - 現在 Gunma University Graduate School of Health Science Laboratory Science (Basic laboratory science)
2012/04 - 2023/03 Jichi Medical University School of Medicine, Department of Biochemistry Assistant Professor
2006/06 - 2012/03 NAIST Department of Bioscience Assistant Professor
2002/04 - 2006/05 St. Jude Children's Research Hospital Department of Tumor Cell Biology Research Associate
1998/04 - 2002/03 Jichi Medical University School of Medicine Research Assistant

Awards (1)：

2012/01 - 公益財団法人武田科学振興財団ライフサイエンス研究奨励助成発がんシグナルと細胞死を制御する新規GTP結合蛋白質の機能解析

Association Membership(s) (2)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY

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