2018 - 2021 Development of periodontal tissue regenerative therapy by using neural crest-derived MSCs and cell clumps culture technique
2016 - 2019 Development of a xeno-free induction and maintenance protocol for MSCs from PSCs
2016 - 2018 Identification of the cell-of-origin of ectopic bones using lineage tracing mice
2016 - 2018 Induction of tendon/ligament progenitor cells from human iPSCs
2015 - 2018 Investigation of functional roles of mutant IDH as specific mutations in cartilage-forming tumors and its application for the development of treatment
2015 - 2017 Functional analyses of mutant NLRP3 on the growth and differentiation of growth plate chondrocytes
2015 - 2017 Induction of corneal endothelial like cells from human pluripotent stem cells through derived neural crest cells.
2014 - 2016 Derivation of human PSC-derived mesodermal cells
2013 - 2016 Analysis of fibrodysplasia ossificans progressive by using iPSCs
2012 - 2015 Investigation for the pathomechanism of cartilage-forming tumors by whole exome sequencing
2012 - 2014 Establishment of canine iPS cells for the study of disease-model dogs
2011 - 2012 Establishment of the assay system of drug screening for fibrodysplasia ossificans progressiva
2009 - 2010 Functional analysis of BMP binding protein, Cv2, in nephorogenesis
Pan Gao, Mikihito Kajiya, Souta Motoike, Makoto Ikeya, Jingmei Yang. Application of mesenchymal stem/stromal cells in periodontal regeneration: Opportunities and challenges. The Japanese dental science review. 2024. 60. 95-108
Megumi Yokomizo-Goto, Nana Takenaka-Ninagawa, Chengzhu Zhao, Clémence Kiho Bourgeois Yoshioka, Mayuho Miki, Souta Motoike, Yoshiko Inada, Denise Zujur, William Theoputra, Yonghui Jin, et al. Distinct muscle regenerative capacity of human induced pluripotent stem cell-derived mesenchymal stromal cells in Ullrich congenital muscular dystrophy model mice. Stem cell research & therapy. 2024. 15. 1. 340-340
Pan Gao, Yoshiko Inada, Akitsu Hotta, Hidetoshi Sakurai, Makoto Ikeya. iMSC-mediated delivery of ACVR2B-Fc fusion protein reduces heterotopic ossification in a mouse model of fibrodysplasia ossificans progressiva. Stem cell research & therapy. 2024. 15. 1. 83-83
Ziadoon Al-Akashi, Denise Zujur, Daisuke Kamiya, Tomohisa Kato, Toru Kondo, Makoto Ikeya. Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification. Frontiers in Cell and Developmental Biology. 2023. 11
