2018 - 2021 Development of periodontal tissue regenerative therapy by using neural crest-derived MSCs and cell clumps culture technique
2016 - 2019 Development of a xeno-free induction and maintenance protocol for MSCs from PSCs
2016 - 2018 Identification of the cell-of-origin of ectopic bones using lineage tracing mice
2016 - 2018 Induction of tendon/ligament progenitor cells from human iPSCs
2015 - 2018 Investigation of functional roles of mutant IDH as specific mutations in cartilage-forming tumors and its application for the development of treatment
2015 - 2017 Functional analyses of mutant NLRP3 on the growth and differentiation of growth plate chondrocytes
2015 - 2017 Induction of corneal endothelial like cells from human pluripotent stem cells through derived neural crest cells.
2014 - 2016 Derivation of human PSC-derived mesodermal cells
2013 - 2016 Analysis of fibrodysplasia ossificans progressive by using iPSCs
2012 - 2015 Investigation for the pathomechanism of cartilage-forming tumors by whole exome sequencing
2012 - 2014 Establishment of canine iPS cells for the study of disease-model dogs
2011 - 2012 Establishment of the assay system of drug screening for fibrodysplasia ossificans progressiva
2009 - 2010 Functional analysis of BMP binding protein, Cv2, in nephorogenesis
1998 - 2000 背側神経管で発現するWnt遺伝子(Wnt-1及びWnt-3a)の機能解析
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Papers (76)：
Ziadoon Al-Akashi, Denise Zujur, Daisuke Kamiya, Tomohisa Kato, Toru Kondo, Makoto Ikeya. Selective vulnerability of human-induced pluripotent stem cells to dihydroorotate dehydrogenase inhibition during mesenchymal stem/stromal cell purification. Frontiers in Cell and Developmental Biology. 2023. 11
Keisuke Mizuno, Hiroe Ohnishi, Masayoshi Yoshimatsu, Chengzhu Zhao, Yasuyuki Hayashi, Fumihiko Kuwata, Shinji Kaba, Hideaki Okuyama, Yoshitaka Kawai, Nao Hiwatashi, et al. Laryngeal Cartilage Regeneration of Nude Rats by Transplantation of Mesenchymal Stem Cells Derived from Human-Induced Pluripotent Stem Cells. Cell Transplantation. 2023. 32. 096368972311784-096368972311784
Ryosuke Ikeguchi, Tomoki Aoyama, Mai Tanaka, Takashi Noguchi, Maki Ando, Koichi Yoshimoto, Daichi Sakamoto, Terunobu Iwai, Yudai Miyazaki, Shizuka Akieda, et al. Nerve regeneration using the Bio 3D nerve conduit fabricated with spheroids. Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs. 2022. 25. 4. 289-297
Naoki Yamada, Chengzhu Zhao, Akira Ito, Tianshu Wang, Akihiro Nakahata, Nan Liang, Taiki Nakajima, Mai Tanaka, Shizuka Akieda, Koichi Nakayama, et al. Peripheral nerve regeneration in a rat crushed sciatic nerve model: Using a Bio 3D sheets generated from human iPSC-derived mesenchymal stromal cells. 2019
