Rchr
J-GLOBAL ID:201401058009175950   Update date: Oct. 22, 2024

Kazuhiro Maeshima

マエシマカズ ヒロ | Kazuhiro Maeshima
Affiliation and department:
Job title: 教授
Other affiliations (1):
  • RIKEN  Visiting Scientist
Homepage URL  (2): http://maeshima-lab.sakura.ne.jphttp://maeshima-lab.sakuraweb.com
Research field  (5): Biophysics ,  Cell biology ,  Molecular biology ,  Nanobioscience ,  Nanomaterials
Research keywords  (26): 染色体 ,  ゲノム ,  核酸 ,  生体分子 ,  ヒトゲノム ,  構造 ,  電子顕微鏡 ,  クロマチン ,  核膜 ,  細胞核 ,  イメージング ,  コンデンシン ,  生物物理 ,  トポイソメラーゼII ,  ライブイメージング ,  X線 ,  分裂期染色体 ,  遺伝学 ,  核膜孔 ,  生体高分子 ,  生体生命情報学 ,  高次構造 ,  ナノ構造解析 ,  生細胞イメージング ,  位相回復 ,  X線回折顕微法
Research theme for competitive and other funds  (22):
  • 2024 - 2029 超解像イメージングで明らかにするクロマチンドメインとその細胞機能制御
  • 2023 - 2026 A novel fluorescence anisotropy imaging for imaging nano-scale LLPS in living cells
  • 2020 - 2025 Genome modality: understanding physical properties of the genome
  • 2020 - 2025 Modality of nucleosome dynamics
  • 2021 - 2024 新規ヌクレオソームイメージングを用いた生細胞におけるクロマチンの高次構造の解明
Show all
Papers (105):
  • Katsuhiko Minami, Satoru Ide, Kako Nakazato, Kazunari Kaizu, Koichi Higashi, Sachiko Tamura, Atsushi Toyoda, Koichi Takahashi, Ken Kurokawa, Kazuhiro Maeshima. Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells. bioRxiv. 2024
  • Shiori Iida, Satoru Ide, Sachiko Tamura, Masaki Sasai, Tomomi Tani, Tatsuhiko Goto, Michael Shribak, Kazuhiro Maeshima. Orientation-independent-DIC imaging reveals that a transient rise in depletion attraction contributes to mitotic chromosome condensation. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 36. e2403153121
  • Kayo Hibino, Yuji Sakai, Sachiko Tamura, Masatoshi Takagi, Katsuhiko Minami, Toyoaki Natsume, Masa A Shimazoe, Masato T Kanemaki, Naoko Imamoto, Kazuhiro Maeshima. Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes. Nature communications. 2024. 15. 1. 7152-7152
  • Adilgazy Semeigazin, Shiori Iida, Katsuhiko Minami, Sachiko Tamura, Satoru Ide, Koichi Higashi, Atsushi Toyoda, Ken Kurokawa, Kazuhiro Maeshima. Behaviors of nucleosomes with mutant histone H4s in euchromatic domains of living human cells. Histochemistry and cell biology. 2024
  • Aoi Otsuka, Katsuhiko Minami, Koichi Higashi, Akane Kawaguchi, Sachiko Tamura, Satoru Ide, Michael J Hendzel, Ken Kurokawa, Kazuhiro Maeshima. Chromatin organization and behavior in HRAS-transformed mouse fibroblasts. Chromosoma. 2024
more...
MISC (46):
  • 井手 聖, 前島 一博. 相分離モデルで理解する転写制御〜核小体と転写コンデンセート〜. 生体の科学. 2023. 74. 234-239
  • 飯田史織, 前島一博. 生きた細胞のなかのヌクレオソームの動きをみる. 現代化学 3月号. 2023. 624. 51-53
  • 飯田 史織, 前島 一博. 【DNAの物性から理解するゲノムモダリティ】核内クロマチンの物理的な性質. 細胞. 2022. 54. 11. 624-627
  • 島添 將誠, 井手 聖, 前島 一博. 【セントラルドグマの新常識 転写・翻訳の驚きの新機構と再定義されるDNA・RNA・タンパク質の世界】(第1章)DNAの新常識 物性から迫るクロマチンの実像 相分離するクロマチンは液体か?固体か?. 実験医学. 2022. 40. 12. 1850-1859
  • 井手 聖, 前島 一博. 【今、解き明かされつつある液-液相分離による生体機能制御】核内構造体と液-液相分離 核小体と転写コンデンセートを中心に. 生化学. 2022. 94. 4. 485-493
more...
Books (7):
  • How small numbers of long genomic DNA are stored in cells
    Springer, Singapore 2018
  • 遺伝子発現制御機構
    東京化学同人 2017
  • 少数性生物学の世界
    日本評論社 2017
  • Combination approach of live-cell imaging and computational modeling toward further comprehensive understanding genome, chromatin and epigenetics
    Academic 2017
  • Dynamic chromatin folding in the cell
    Academic Press 2017 ISBN:0128034807
more...
Lectures and oral presentations  (59):
  • Chromatin organization and behavior during the cell cycle revealed by single-nucleosome imaging/tacking
    (ICTS Meeting “Interdisciplinary aspects of chromatin organization and gene regulation”, Bangalore, India. 2024)
  • Linker histone H1 serves as liquid-like “glue” of the chromatin domain.
    (JSCB Annual Meeting (細胞生物学会年会), Symposium 3S-Am (Session organizer) ”Chromatin structure and genome modality”. 2024)
  • Replication-dependent histone (Repli-Histo) labeling specifically visualizes physical properties of euchromatin/heterochromatin in living human cells.
    (S24 “Chromatin Dynamics and Imaging” Session Chair. IUPAB 2024 2024)
  • 細胞内のクロマチンは固体的か液体的か?
    (NIKONシリーズセミナー「相分離」(Webinar) 第5回 2024)
  • Chromatin organization and behavior during the cell cycle revealed by single-nucleosome imaging/tacking
    (LRBGE Seminar @ National Cancer Institute, NIH. 2024)
more...
Education (3):
  • 1995 - 1999 Osaka University
  • 1993 - 1995 Osaka University
  • 1989 - 1993 University of Tsukuba
Professional career (1):
  • Ph.D. (Osaka University)
Work history (12):
  • 2024/04 - 現在 Head, Department of Chromosome Science, National Institute of Genetics
  • 2023/04 - 現在 Genetics Course, Graduate Institute for Advanced Studies, SOKENDAI Professor
  • 2019/04 - 現在 National Institute of Genetics Department of Chromosome Science Professor
  • 2022/04 - 2024/03 National Institute of Genetics Assistant to the Director-General
  • 2009/04 - 2023/03 SOKENDAI Department of Genetics, School of Life Science Professor
Show all
Awards (1):
  • 2016/05 - Kihara Memorial Foundation 2015 Kihara Memorial Foundation Academic Award
Association Membership(s) (5):
THE JAPANESE SOCIETY FOR SYNCHROTRON RADIATION RESEARCH ,  THE BIOPHYSICAL SOCIETY OF JAPAN ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  American Society for Cell Biology
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page