2019 - 2021 Understanding how the transcription machinery regulates chromatin dynamics
2016 - 2019 Heterochromatin dynamics revealed by single nucleosome imaging
2011 - 2016 Spying minority in biological phenomena -Toward bridging dynamics between individual and ensemble processes-
2011 - 2015 Small number issues in the genome biology
2011 - 2013 Dynamics of human genome DNA in living cells revealed by nucleosome imaging
2010 - 2012 Cryo-bioimaging by using coherent X-ray diffraction
2010 - 2012 Development of a novel genome mapping method by using homologous recombination protein
2010 - 2011 増殖相と分化相におけるクロマチン構造基盤の解析
2008 - 2010 物理化学的手法を用いたヒトゲノムの折り畳み構造の統合的解析
2008 - 2009 DECODEシステムの基礎基盤となる核内クロマチン構造の解析
2007 - 2009 Nanostructure Analysis of Biospecimens with Coherent X-ray Diffraction Microscopy
2007 - 2008 Understanding of mechanism of nuclear pore formation during cell cycle.
2007 - 2008 X線をもちいた核ゲノム構造の解析
2006 - 2007 Role of Nuclear Pore Complexes on Nuclear Organization
2006 - 2007 分裂間期核の核膜孔複合体形成におけるメンブレントラフィックの役割の解析
2005 - 2006 分裂期染色体の構造解析に基づくヒトゲノムの高次機能の解明
2005 - 2006 分裂期染色体の構造解析(クロマチンイメージング)に基づく核ゲノム機能の解明
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Papers (105):
Katsuhiko Minami, Satoru Ide, Kako Nakazato, Kazunari Kaizu, Koichi Higashi, Sachiko Tamura, Atsushi Toyoda, Koichi Takahashi, Ken Kurokawa, Kazuhiro Maeshima. Replication-dependent histone (Repli-Histo) labeling dissects the physical properties of euchromatin/heterochromatin in living human cells. bioRxiv. 2024
Shiori Iida, Satoru Ide, Sachiko Tamura, Masaki Sasai, Tomomi Tani, Tatsuhiko Goto, Michael Shribak, Kazuhiro Maeshima. Orientation-independent-DIC imaging reveals that a transient rise in depletion attraction contributes to mitotic chromosome condensation. Proceedings of the National Academy of Sciences of the United States of America. 2024. 121. 36. e2403153121
Kayo Hibino, Yuji Sakai, Sachiko Tamura, Masatoshi Takagi, Katsuhiko Minami, Toyoaki Natsume, Masa A Shimazoe, Masato T Kanemaki, Naoko Imamoto, Kazuhiro Maeshima. Single-nucleosome imaging unveils that condensins and nucleosome-nucleosome interactions differentially constrain chromatin to organize mitotic chromosomes. Nature communications. 2024. 15. 1. 7152-7152
Adilgazy Semeigazin, Shiori Iida, Katsuhiko Minami, Sachiko Tamura, Satoru Ide, Koichi Higashi, Atsushi Toyoda, Ken Kurokawa, Kazuhiro Maeshima. Behaviors of nucleosomes with mutant histone H4s in euchromatic domains of living human cells. Histochemistry and cell biology. 2024
Aoi Otsuka, Katsuhiko Minami, Koichi Higashi, Akane Kawaguchi, Sachiko Tamura, Satoru Ide, Michael J Hendzel, Ken Kurokawa, Kazuhiro Maeshima. Chromatin organization and behavior in HRAS-transformed mouse fibroblasts. Chromosoma. 2024
How small numbers of long genomic DNA are stored in cells
Springer, Singapore 2018
遺伝子発現制御機構
東京化学同人 2017
少数性生物学の世界
日本評論社 2017
Combination approach of live-cell imaging and computational modeling toward further comprehensive understanding genome, chromatin and epigenetics
Academic 2017
Dynamic chromatin folding in the cell
Academic Press 2017 ISBN:0128034807
Chromatin organization and behavior during the cell cycle revealed by single-nucleosome imaging/tacking
(ICTS Meeting “Interdisciplinary aspects of chromatin organization and gene regulation”, Bangalore, India. 2024)
Linker histone H1 serves as liquid-like “glue” of the chromatin domain.
(JSCB Annual Meeting (細胞生物学会年会), Symposium 3S-Am (Session organizer) ”Chromatin structure and genome modality”. 2024)
Replication-dependent histone (Repli-Histo) labeling specifically visualizes physical properties of euchromatin/heterochromatin in living human cells.
(S24 “Chromatin Dynamics and Imaging” Session Chair. IUPAB 2024 2024)
Chromatin organization and behavior during the cell cycle revealed by single-nucleosome imaging/tacking
(LRBGE Seminar @ National Cancer Institute, NIH. 2024)
2024/04 - 現在 Head, Department of Chromosome Science, National Institute of Genetics
2023/04 - 現在 Genetics Course, Graduate Institute for Advanced Studies, SOKENDAI Professor
2019/04 - 現在 National Institute of Genetics Department of Chromosome Science Professor
2022/04 - 2024/03 National Institute of Genetics Assistant to the Director-General
2009/04 - 2023/03 SOKENDAI Department of Genetics, School of Life Science Professor
2020/04 - 2022/03 National Institute of Genetics Department of Chromosome Science Head
2009/04 - 2019/03 National Institute of Genetics Biological Macromolecules Laboratory, Structural Biology Center Professor
2007/04 - 2009/03 RIKEN
2005/10 - 2007/03 RIKEN
2004/06 - 2005/09 理化学研究所 細胞核機能研究室 基礎科学特別研究員
1999/05 - 2004/06 スイス ジュネーブ大学 分子生物・生化学科 ポスドク研究員
1996/04 - 1999/03 Osaka University JSPS Fellow DC1
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Awards (1):
2016/05 - Kihara Memorial Foundation 2015 Kihara Memorial Foundation Academic Award
Association Membership(s) (5):
THE JAPANESE SOCIETY FOR SYNCHROTRON RADIATION RESEARCH
, THE BIOPHYSICAL SOCIETY OF JAPAN
, JAPAN SOCIETY FOR CELL BIOLOGY
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, American Society for Cell Biology