Rchr
J-GLOBAL ID：201401058529701132   Update date: Apr. 20, 2024

Nasu Ryo

Nasu Ryo
Affiliation and department：
Chiba University Graduate School of Medicine, Department of Experimental Immunology

About Chiba University Graduate School of Medicine, Department of Experimental Immunology


Research field  (2)： Immunology ,  Tumor biology
Research keywords  (5)： cancer immunity ,  CD8T cells ,  tumor-draining lymph nodes ,  CD69 ,  cancer stem cells
Research theme for competitive and other funds  (16)：
  • 2024 - 2027 所属リンパ節における腫瘍特異的CD8T細胞の分化運命決定を制御する免疫療法の開発
  • 2022 - 2027 Mechanisms of immune homeostasis and responses based on T cell mediated self-recognition
  • 2021 - 2024 幹細胞様CD8T細胞を起点とする腫瘍内T細胞分化の理解に基づくがん免疫療法の開発
  • 2020 - 2022 CD69分子を標的とした新規のがん免疫療法開発へ向けた基盤研究
  • 2018 - 2021 Development of new cancer immunotherapy that targets the CD69-Myl9/12 system
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Papers (30)：
  • Ryo Koyama-Nasu, Motoko Y. Kimura, Masahiro Kiuchi, Ami Aoki, Yangsong Wang, Yukiyoshi Mita, Ichita Hasegawa, Yukihiro Endo, Atsushi Onodera, Kiyoshi Hirahara, et al. CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes. Cancer Immunology Research. 2023. 11. 8. 1085-1099
  • Asuka Shibamiya, Yurie Miyamoto-Nagai, Shuhei Koide, Motohiko Oshima, Ola Rizq, Kazumasa Aoyama, Yaeko Nakajima-Takagi, Rei Kato, Kensuke Kayamori, Yusuke Isshiki, et al. The pathogenetic significance of exhausted T cells in a mouse model of mature B cell neoplasms. Cancer Immunology, Immunotherapy. 2023. 72. 8. 2635-2648
  • Ryo Koyama-Nasu, Yangsong Wang, Ichita Hasegawa, Yukihiro Endo, Toshinori Nakayama, Motoko Y Kimura. The cellular and molecular basis of CD69 function in anti-tumor immunity. International Immunology. 2022. 34. 11. 555-561
  • Murshed H. Sarkar, Ryoji Yagi, Yukihiro Endo, Ryo Koyama-Nasu, Yangsong Wang, Ichita Hasegawa, Toshihiro Ito, Ilkka S. Junttila, Jinfang Zhu, Motoko Y. Kimura, et al. IFNγ suppresses the expression of GFI1 and thereby inhibits Th2 cell proliferation. PLOS ONE. 2021. 16. 11. e0260204-e0260204
  • Ayaka Hara, Ryo Koyama-Nasu, Mariko Takami, Takahide Toyoda, Takahiro Aoki, Fumie Ihara, Masayoshi Kobayashi, Seiichiro Hirono, Tomoo Matsutani, Toshinori Nakayama, et al. CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy. Cancer Immunology, Immunotherapy. 2020. 70. 5. 1239-1254
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MISC (15)：
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Books (1)：
  • miRNAの最新知識~基礎領域から診断・治療応用まで~
    医薬ジャーナル社 2017
Lectures and oral presentations  (27)：
  • CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy
    (第78回日本癌学会学術総会 2019)
  • CD1d expression in glioblastoma is a promising target for NKT cell-based cancer immunotherapy
    (EMBO workshop CD1-MR1 2019)
  • Inhibition of acetyl-CoA carboxylase enhances memory Th2 cell generation and Th2 mediated anti-tumor immunity
    (第23回日本がん免疫学会総会 2019)
  • 膠芽腫に発現するCD1d 分子はNKT 細胞を用いた免疫療法における有望な標的となる
    (第23回日本がん免疫学会総会 2019)
  • がん免疫療法の新たなターゲットとしてのCD69の可能性
    (第23回日本がん免疫学会総会 2019)
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Education (2)：
  • - 2001 東京大学大学院 農学生命科学研究科 応用生命工学専攻
  • - 1996 The University of Tokyo
Professional career (1)：
  • 博士 (農学) (東京大学)
Work history (7)：
  • 2021 - 現在 Chiba University
  • 2016 - Chiba University Graduate School of Medicine
  • 2015 - Tokai University School of Medicine
  • 2013 - Kyoto Prefectural University of Medicine Graduate School of Medical Science
  • 2007 - The University of Tokyo Institute of Molecular and Cellular Biosciences
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Committee career (2)：
  • 2007 - 2013 分子細胞生物学研究所 男女共同参画ワーキンググループ委員
  • 2007 - 2013 分子細胞生物学研究所 RI 委員
Association Membership(s) (2)：
THE JAPANESE SOCIETY FOR IMMUNOLOGY ,  THE JAPANESE CANCER ASSOCIATION
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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