Rchr
J-GLOBAL ID:201401066323054346
Update date: Oct. 16, 2024
Iwasaki Yusaku
イワサキ ユウサク | Iwasaki Yusaku
Affiliation and department:
Homepage URL (2):
http://kaken.nii.ac.jp/d/r/60528420.ja.html
,
https://www2.kpu.ac.jp/life_environ/animal_sci/
Research field (4):
Physiology
, Nutrition and health science
, Food sciences
, Clinical pharmacy
Research keywords (20):
求心性迷走神経
, オキシトシン
, 過食
, 香辛料
, アルロース
, 希少糖
, 体温調節
, TRPV1
, TRPA1
, 食欲不振
, インスリン感受性
, 糖尿病
, 肥満
, グレリン
, GLP-1
, 迷走神経
, 摂食
, グルコース
, インスリン
, nodose ganglion
Research theme for competitive and other funds (16):
- 2023 - 2026 Strategy for prevention and reduction of aspiration pneumonia and extension of healthy life expectancy by activation of dietary neuro-immune system
- 2023 - 2025 The investigation of the effect and underlying mechanism by which the intake of sugars and fats attenuates the beneficial effects after meals.
- 2020 - 2023 Investigation of the role of <GLP-1 - autonomic nerves reflex - adrenal adrenaline> axis on diet-induced thermogenesis
- 2020 - 2022 The fructose paradox: analysis of the molecular mechanisms that inhibit the benefits of fructose
- 2019 - 2022 Central and organ mechanisms for anti-obesity/diabetes effects of rare sugar allulose
- 2020 - 2022 脳・全身機能を調節する<求心性迷走神経→脳>軸の基盤機構解明と機能性食品への応用
- 2019 - 2021 Establishing appetitive vagal afferent nerve for ameliorating anorexia, frailty, cancer and depression
- 2021 - 2021 コロナ感染症に立ち向かう健康作りに貢献する食事リズムの重要性検証とその支援技術の開発
- 2017 - 2020 Establishing orexigenic vagal afferent subclass and its physiological and pharmacological roles for treating anorexia
- 2016 - 2018 Molecular mechanism for highly sensitive response to peripheral hormones in hypothalamic neurons and homeostatic role
- 2014 - 2018 Insulin action on vagal afferents and its regulation in feeding and metabolisms
- 2014 - 2017 GLP-1 and insulin synergize to activate vagal afferent nerves leading to central regulation of metabolism, feeding and blood pressure
- 2012 - 2014 Vagal afferent-mediated coupling of peripheral factor sensing to brain transmission and feeding regulation
- 2011 - 2014 Regulation by nesfatin and oxytocin of feeding, metabolism and circadian rhythm, as a basis for treating life style-related diseases
- 2010 - 2011 Cellular and molecular mechanism of hormone sensing on vagal afferents and its linking to the feeding
- 2005 - 2007 温度感受性受容体に働く食品成分の探索とエネルギー代謝の作用の解析
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Papers (59):
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Kento Ohbayashi, Yudai Sugiyama, Taichi Nohmi, Kazusa Nishimura, Tetsuya Nakazaki, Yo-Ichiro Sato, Takehiro Masumura, Yusaku Iwasaki. Anekomochi glutinous rice provides low postprandial glycemic response by enhanced insulin action via GLP-1 release and vagal afferents activation. The journal of physiological sciences : JPS. 2024. 74. 1. 47-47
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Koki Nishida, Shinji Ueno, Yusuke Seino, Shihomi Hidaka, Naoya Murao, Yuki Asano, Haruki Fujisawa, Megumi Shibata, Takeshi Takayanagi, Kento Ohbayashi, et al. Impaired Fat Absorption from Intestinal Tract in High-Fat Diet Fed Male Mice Deficient in Proglucagon-Derived Peptides. Nutrients. 2024. 16. 14. 2270-2270
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Yuriko Oi-Kano, Tsuyoshi Goto, Haruya Takahashi, Yusaku Iwasaki, Teruo Kawada. Effect of Oleuropein on Anti-Obesity and Uncoupling Protein 1 Level in Brown Adipose Tissue in Mild Treadmill Walking Rats with Diet-Induced Obesity. Journal of nutritional science and vitaminology. 2024. 70. 3. 193-202
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Quan Yingyue, Kenji Sugawara, Harumi Takahashi, Norihide Yokoi, Kento Ohbayashi, Yusaku Iwasaki, Susumu Seino, Wataru Ogawa. Stimulatory effect of imeglimin on incretin secretion. Journal of diabetes investigation. 2023. 14. 6. 746-755
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Wanxin Han, Lei Wang, Kento Ohbayashi, Masakazu Takeuchi, Libbey O'Farrell, Tamer Coskun, Yermek Rakhat, Daisuke Yabe, Yusaku Iwasaki, Yutaka Seino, et al. Glucose-dependent insulinotropic polypeptide counteracts diet-induced obesity along with reduced feeding, elevated plasma leptin and activation of leptin-responsive and proopiomelanocortin neurons in the arcuate nucleus. Diabetes, obesity & metabolism. 2023. 25. 6. 1534-1546
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MISC (38):
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岩崎有作. 糖尿病の成因である過食および摂食リズム異常と求心性迷走神経機能との関連. 糖尿病学の進歩. 2024. 58th
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岩崎有作, 中村唱乃, 能美太一, 嵯峨根里穂, 大林健人, 宮崎麻衣子, 金武祚. 食事性GABAの求心性迷走神経を介した飽満感増強作用. 糖尿病(Web). 2023. 66. Suppl
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大林健人, 岩崎有作. 膵インスリンは腸GLP-1と協働して求心性迷走神経を賦活化し血糖降下作用を増強する. 糖尿病(Web). 2023. 66. Suppl
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権映月, 権映月, 菅原健二, 高橋晴美, 横井伯英, 横井伯英, 大林健人, 岩崎有作, 清野進, 小川渉. The effects of imeglimin on incretin secretion. 糖尿病(Web). 2023. 66. Suppl
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射場拳虎, 岩崎有作. 希少糖アルロースによる腸ホルモンGLP-1分泌促進は抗不安・社会性向上作用を誘導する. 糖尿病(Web). 2023. 66. Suppl
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Education (3):
- 2005 - 2008 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
- 2003 - 2005 University of Shizuoka Graduate School of Nutritional and Environmental Sciences
- 1999 - 2003 University of Shizuoka School of Food and Nutritional Sciences Department of Food Science
Professional career (1):
Work history (6):
Awards (14):
- 2024/09 - 乳の学術連合 牛乳乳製品健康科学学術研究2023年度研究 最優秀賞
- 2023/04 - 国際希少糖学会 第8回国際希少糖学会優秀ポスター賞 Release of intestinal hormone GLP-1 by D-allulose ameliorates hyperglycemia through gut - vagal afferent nerves - brain axis
- 2022/12 - 日本肥満学会 日本肥満学会学術奨励賞 食事-ホルモン-求心性迷走神経軸による摂食・代謝調節から肥満症改善へ
- 2020/03 - 日本生理学会環境生理学グループディナー 第24回久野寧記念賞
- 2020/03 - 第24回安藤百福賞「発明発見奨励賞」 ゼロカロリー甘味料D-アルロースの満腹感誘導、肥満・糖尿病改善作用の発見
- 2017/11 - 2017年度ひと・健康・未来助成研究発表会優秀賞
- 2016/11 - 第6回国際希少糖希少糖学会ベストポスター賞
- 2016 - 日本生理学会 奨励賞
- 2015/04 - 日本内分泌学会 2015年度若手研究奨励賞(YIA)
- 2014/11 - 自治医科大学 平成26年度自治医科大学医学部優秀論文賞
- 2011/09 - 日本肥満学会 Young Investigator Award
- 2011/05 - 日本農芸化学会 Bioscience, Biotechnology, and Biochemistry 2010年論文賞
- 2010/09 - 自治医科大学 第9回自治医科大学シンポジウム ポスターセッション優秀賞
- 2006/11 - 第2回中部食品科学研究交流会・FSF合同研究集会 セミナーバトル2位
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