J-GLOBAL ID:201401075357557222   Update date: Jun. 07, 2019

Kenji Fukui

フクイ ケンジ | Kenji Fukui
Affiliation and department:
Homepage URL  (1): https://scholar.google.co.jp/citations?hl=ja&user=bq7-z90AAAAJ
Research field  (3): Functional biochemistry ,  Applied microbiology ,  Molecular biology
Research keywords  (1): MutS2
Research theme for competitive and other funds  (1):
  • 2008 - 2010 Structural and functional analyses on a novel mechanism of homologous recombination suppression.
Papers (29):
  • Minobe A, Fukui K, Yonezu H, Ohshita K, Mizobuchi S, Morisawa T, Hakumai Y, Yano T, Ashiuchi M, Wakamatsu T. Biochemical characterization of mismatch-binding protein MutS1 and nicking endonuclease MutL from a euryarchaeon Methanosaeta thermophila. DNA Repair. 2019. 75. 29-38
  • Kenji Fukui, Akiko Harada, Taisuke Wakamatsu, Ai Minobe, Koki Ohshita, Makoto Ashiuchi, and Takato Yano. The GIY-YIG endonuclease domain of Arabidopsis MutS homolog 1 specifically binds to branched DNA structures. FEBS Letters. 2018. 592. 24. 4066-4077
  • Yuki Fujii, Masao Inoue, Kenji Fukui, Seiki Kuramitsu, and Ryoji Masui. Resistance to UV Irradiation Caused by Inactivation of nurA and herA Genes in Thermus thermophilus. J. Bacteriol. 2018. 200. 16. e00201-e00218
  • Kenji Fukui, Seiki Baba, Takashi Kumasaka, Takato Yano. Multiple zinc ions maintain the open conformation of the catalytic site in the DNA mismatch repair endonuclease MutL from Aquifex aeolicus. FEBS Lett. 2018. 592. 9. 1611-1619
  • Kenji Fukui, Hitoshi Iino, Seiki Baba, Takashi Kumasaka, Seiki Kuramitsu, and Takato Yano. Crystal structure and DNA-binding property of the ATPase domain of bacterial mismatch repair endonuclease MutL from Aquifex aeolicus. Biochim Biophys Acta. 2017. 1865. 9. 1178-1187
MISC (3):
  • Kenji Fukui. Regulatory mechanism for DNA mismatch repair endonuclease. Seikagaku. 2015. 87. 2. 212-217
  • Kenji Fukui, Taisuke Wakamatsu, Yoshihiro Agari, Ryoji Masui, Seiki Kuramitsu. Inactivation of the DNA repair genes mutS, mutL or the anti-recombination gene mutS2 leads to activation of vitamin B1 biosynthesis genes. Vitamins (Japan). 2014. 88. 9. 459-461
  • Kenji Fukui, Atsuhiro Shimada, Hitoshi Iino, Ryoji Masui, Seiki Kuramitsu. Biochemical Properties of MutL, a DNA Mismatch Repair Endonuclease. DNA Repair - on the pathways to fixing DNA damage and errors. 2011. 123-142
Education (1):
  • 1998 - 2002 Osaka University Department of Biology
Work history (5):
  • 2005/04 - 2007/03 Osaka University JSPS Fellow DC2
  • 2007/04 - 2012/10 RIKEN Researcher
  • 2012/11 - 2013/03 Osaka University Specially Appointed Assistant Professor
  • 2013/04 - 2014/03 Transgenic Inc. Researcher
  • 2014/04 - 現在 Osaka Medical College Assistant Professor
Awards (2):
  • 2012/03 - RIKEN RIKEN Research Incentive Award
  • 2005/10 - The JB Prize Thermus thermophilus MutS2, a MutS paralogue, possesses an endonuclease activity promoted by MutL
Association Membership(s) (1):
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