Rchr
J-GLOBAL ID:201401092855808609   Update date: May. 05, 2024

Uchibori ryosuke

ウチボリ リヨウスケ | Uchibori ryosuke
Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/20458285.ja.html
Research field  (2): Tumor diagnostics and therapeutics ,  Hematology and oncology
Research keywords  (7): キメラ抗原受容体 ,  多発性骨髄腫 ,  B細胞性腫瘍 ,  細胞治療 ,  遺伝子治療 ,  癌 ,  間葉系幹細胞
Research theme for competitive and other funds  (5):
  • 2019 - 2022 Development of selective regulatory system for proliferation and persistence of CAR-T cells
  • 2016 - 2018 Development of CD269-CAR T cells for the adoptive immunotherapy of multiple myeloma.
  • 2012 - 2015 Development of gene therapy for refractory non-Hodgkin lymphoma using T-cells expressing a chimeric antigen receptor
  • 2012 - 2014 Development of switch promoters driven by activation signals from the chimeric antigen receptors.
  • 2009 - 2011 Development of gene therapy using bone-marrow-derived mesenchymal stem cells
Papers (46):
  • Yoshihide Sehara, Yuki Hashimotodani, Ryota Watano, Kenji Ohba, Ryosuke Uchibori, Kuniko Shimazaki, Kensuke Kawai, Hiroaki Mizukami. Adeno-associated Virus-mediated Ezh2 Knockdown Reduced the Increment of Newborn Neurons Induced by Forebrain Ischemia in Gerbil Dentate Gyrus. Molecular neurobiology. 2024
  • Somsak Prasongtanakij, Sarinthip Preedagasamzin, Bunyada Jittorntrum, Usanarat Anurathapan, Teeraya Puavilai, Pimjai Niparuck, Pichika Chantrathammachart, Thanakrit Piyajaroenkij, Kitipong Uaesoontrachoon, Ryosuke Uchibori, et al. Cytotoxicity and exhaustion markers of chimeric antigen receptor T cells targeting BCMA in multiple myeloma cell lines between patients and healthy donors. European Journal of Haematology. 2023
  • 内堀 亮介, 大嶺 謙. 【遺伝子治療update】CAR-T細胞療法の現状と課題. BIO Clinica. 2022. 37. 6. 525-529
  • Ken Ohmine, Ryosuke Uchibori. Novel immunotherapies in multiple myeloma. International Journal of Hematology. 2022. 115. 6. 799-810
  • 内堀 亮介, 大嶺 謙. AMLに対するCAR-T療法の開発の現状と新規CD70特異的CAR-T. 血液内科. 2022. 84. 5. 730-736
more...
MISC (30):
  • T. Yoshiba, Y. Saga, Y. Sehara, R. Uchibori, M. Urabe, H. Fujiwara, S. Matsubara, H. Mizukami. Efficient targeting of uterine cervical cancer using AAV vectors encoding CRISPR/Cas9 against HPV-E6 gene. HUMAN GENE THERAPY. 2017. 28. 12. A24-A25
  • Ryosuke Uchibori, Ken Ohmine, Yoshihide Sehara, Masashi Urabe, Hiroaki Mizukami, Junichi Mineno, Kazuto Takesako, Keiya Ozawa. Effect of CAR-T Therapy on Bone Lesions in Myeloma Mouse Model. MOLECULAR THERAPY. 2017. 25. 5. 58-58
  • Hiroaki Mizukami, Tsukasa Ohmori, Ryosuke Uchibori, Yasushi Saga, Masashi Urabe, Akihiro Kume, Yoichi Sakata, Keiya Ozawa. Duration of Factor IX Expression in Macaques Following AAV8-Mediated Liver Transduction. MOLECULAR THERAPY. 2016. 24. S87-S87
  • Masashi Urabe, Ryosuke Uchibori, Akihiro Kume, Hiroaki Mizukami, Keiya Ozawa. The Use of Thymidine Kinase Mutants as a Safeguard Switch for IPS Cells. MOLECULAR THERAPY. 2016. 24. S95-S96
  • Ryosuke Uchibori, Takeshi Teruya, Ken Ohmine, Masashi Urabe, Yasushi Saga, Hiroaki Mizukami, Junichi Mineno, Kazuto Takesako, Keiya Ozawa. CD269 (BCMA)-Specific CAR-Expressing T Cells Dramatically Eradicate Myeloma Cells from Bone Marrow of an Orthotopic Multiple Myeloma Mouse Model. MOLECULAR THERAPY. 2016. 24. S158-S159
more...
Books (1):
  • The biology and therapeutic application of mesenchymal cells
    Wiley Blackwell 2017 ISBN:1118907515
Professional career (1):
  • Ph.D. (Jichi Medocal University)
Work history (3):
  • 2023/04 - 現在 Jichi Medical University
  • 2016/04 - 2023/03 Jichi Medical University
  • 2011 - 2016/03 Jichi Medical University School of Medicine
Awards (4):
  • 2013 - American Society of Gene & Cell Therapy Outstanding Poster Presentation Award
  • 2012/11 - 自治医科大学 自治医科大学医学部最優秀論文賞
  • 2011/04 - 自治医科大学 自治医科大学医学部研究奨励賞
  • 自治医科大学 自治医科大学大学院医学研究科研究奨励賞
Association Membership(s) (4):
AMERICAN SOCIETY OF GENE & CELL THERAPY ,  THE JAPANESE SOCIETY OF HEMATOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  JAPAN SOCIETY OF GENE THERAPY
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