Sato Shinichi

Affiliation and department：

Research field (4)： Biochemistry , Molecular biology , Chemical biology , Bioorganic chemistry

Research theme for competitive and other funds (10)：

2023 - 2026 New technologies for RNA structural regulation that enables the control and analysis of cellular function
2021 - 2025 日本発の革新的バイオ医薬開発を目指した細胞内RNA機能の制御機構の解明と創薬応用
2020 - 2023 Understanding Cellular Function with Short RNAs and Small Molecules
2021 - 2023 Staple核酸を利用した新規核酸医薬機序開拓
2019 - 2021 Staple核酸を用いた新規核酸医薬開発

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Papers (71)：

Hironao Munakata, Yuri Sohma, Kaito Utsumi, Rinka Ohno, Kotaro Ishida, Eiji Morita, Shin-ichi Sato, Masaki Hagihara. Development of triggerable peroxidase-tagged primers for colorimetric DNA detection applicable to various DNA polymerases. Chemistry Letters. 2024. 53. 11
Kenji Yatsuzuka, Yousuke Katsuda, Shin-ichi Sato. Live-Cell Imaging of Multiple Endogenous mRNAs Using RNA Aptamers and Chemical Probes. Springer Nature US. 2024. 2875. 189-204
Hironao Munakata, Yuri Sohma, Kotaro Ishida, Eiji Morita, Shin-ichi Sato, Masaki Hagihara. Triggerable peroxidase-tagged primer enables naked eye monitoring of PCR amplification. Chemistry Letters. 2024. 53. 10
Vaibhav Pal Singh, Shuhei Hirose, Misao Takemoto, Asmaa M. A. S. Farrag, Shin-ichi Sato, Tasuku Honjo, Kenji Chamoto, Motonari Uesugi. Chemoproteomic Identification of Spermidine-Binding Proteins and Antitumor-Immunity Activators. Journal of the American Chemical Society. 2024. 146. 24. 16412-16418
Hyoseok Kim, Changyi Cui, Kohei Toh, Genyir Ado, Tetsuya Ogawa, Yixin Zhang, Shin-ichi Sato, Yong-Beom Lim, Hiroki Kurata, Lu Zhou, et al. Discovery of a self-assembling small molecule that sequesters RNA-binding proteins. Chinese Chemical Letters. 2024. 110135-110135

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MISC (27)：

木田朋輝, 勝田陽介, 北村裕介, 萩原正規, 佐藤慎一, 井原敏弘. Next generation nucleic-acid medicine that suppresses gene expression by XNA’s free pass Staple system. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
五木結愛, 勝田陽介, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. Creation of novel nucleic acid medicine using RNA hacking technology to increase gene expression. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
嘉村匠人, 勝田陽介, 北村祐介, 萩原正規, 佐藤慎一, 井原敏博. A nucleic acid medicine against PAH based on the construction of RNA G-quadruplex structure. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2022. 7th
勝田陽介, 嘉村匠人, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. G-quadruplexを利用したRNA faction検出法の開発. 日本分析化学会講演要旨集. 2018. 67年会. 104-104
渡邉瑞貴, 浅野理沙, 領田優太, KHAMBA Bilon, 薄田晃佑, 飯田圭介, 岩田淳, 佐藤慎一, 長澤和夫, 上杉志成. 脂質生合成を抑制する内因性小分子化合物. 天然有機化合物討論会講演要旨集(Web). 2014. 56th. 85-89(J-STAGE)

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Patents (3)：

Books (11)：

Live-Cell RNA Imaging Methods and Protocols
Springer Nature US 2024
ケミカルバイオロジー化合物集~研究展開のヒント~
オーム社 2018
生細胞内で RNA を操る~RNA ツールと化合物による細胞機能の理解~
生命科学研究レター 2018
ビオチン化体を利用した生化学的標的タンパク質精製法
化学同人 2015
Affinity-based isolation of molecular targets of clinically used drugs
Case Studies in Chemical Biology 2014

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Lectures and oral presentations (65)：

RNA hacking技術に基づいたXNA Stapleによるin vivo遺伝子発現抑制技術の開発
(日本核酸医薬学会第8回年会 2023)
生細胞内でRNAを操る
(日本核酸医薬学会第8回年会 2023)
生細胞内でRNA機能を操作して生命現象を理解する
(久留米工業高等専門学校生物応用化学科セミナー 2022)
Development of Novel Nucleic Acid Drug Technology Involving RNA Higher-Order Structural Changes
(Japanese Society for Chemical Biology 2022)
Gene expression regulation using Staple nucleic acids for the treatment of Parkinson's disease
(Japanese Society for Chemical Biology 2022)

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Committee career (2)：

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