Sato Shinichi

Affiliation and department：

Research field (4)： Biochemistry , Molecular biology , Chemical biology , Bioorganic chemistry

Research theme for competitive and other funds (10)：

2023 - 2026 New technologies for RNA structural regulation that enables the control and analysis of cellular function
2021 - 2025 日本発の革新的バイオ医薬開発を目指した細胞内RNA機能の制御機構の解明と創薬応用
2020 - 2023 Understanding Cellular Function with Short RNAs and Small Molecules
2021 - 2023 Staple核酸を利用した新規核酸医薬機序開拓
2019 - 2021 Staple核酸を用いた新規核酸医薬開発

Show all

Papers (64)：

Yousuke Katsuda, Takuto Kamura, Tomoki Kida, Takeru Saeki, Yua Itsuki, Yuri Kato, Taishi Nakamura, Motohiro Nishida, Yusuke Kitamura, Toshihiro Ihara, et al. In Vivo mRNA Hacking with Staple Oligomers Prevents Myocardial Hypertrophy. 2023
Kohei Toh, Kosuke Nishio, Reiko Nakagawa, Syusuke Egoshi, Masahiro Abo, Amelie Perron, Shin-ichi Sato, Naoki Okumura, Noriko Koizumi, Kosuke Dodo, et al. Chemoproteomic Identification of Blue-Light-Damaged Proteins. Journal of the American Chemical Society. 2022. 144. 44. 20171-20176
Yousuke Katsuda, Shin-ichi Sato, Maimi Inoue, Hisashi Tsugawa, Takuto Kamura, Tomoki Kida, Rio Matsumoto, Sefan Asamitsu, Norifumi Shioda, Shuhei Shiroto, et al. Small molecule-based detection of non-canonical RNA G-quadruplex structures that modulate protein translation. Nucleic Acids Research. 2022. 50. 14. 8143-8153
Genyir Ado, Naotaka Noda, Hue T. Vu, Amelie Perron, Amarjyoti D. Mahapatra, Karla Pineda Arista, Hideaki Yoshimura, Daniel M. Packwood, Fumiyoshi Ishidate, Shin-ichi Sato, et al. Discovery of a phase-separating small molecule that selectively sequesters tubulin in cells. Chemical Science. 2022. 13. 19. 5760-5766
Naotaka Noda, Yejin Jung, Genyir Ado, Yoshiyuki Mizuhata, Masakazu Higuchi, Tetsuya Ogawa, Fumiyoshi Ishidate, Shin-ichi Sato, Hiroki Kurata, Norihiro Tokitoh, et al. Glucose as a Protein-Condensing Cellular Solute. ACS Chemical Biology. 2022. 17. 3. 567-575

ｍore...

MISC (25)：

木田朋輝, 勝田陽介, 北村裕介, 萩原正規, 佐藤慎一, 井原敏弘. Next generation nucleic-acid medicine that suppresses gene expression by XNA’s free pass Staple system. 日本化学会春季年会講演予稿集(Web). 2022. 102nd
五木結愛, 勝田陽介, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. Creation of novel nucleic acid medicine using RNA hacking technology to increase gene expression. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
嘉村匠人, 勝田陽介, 北村祐介, 萩原正規, 佐藤慎一, 井原敏博. A nucleic acid medicine against PAH based on the construction of RNA G-quadruplex structure. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2022. 7th
勝田陽介, 嘉村匠人, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. G-quadruplexを利用したRNA faction検出法の開発. 日本分析化学会講演要旨集. 2018. 67年会. 104-104
渡邉瑞貴, 浅野理沙, 領田優太, KHAMBA Bilon, 薄田晃佑, 飯田圭介, 岩田淳, 佐藤慎一, 長澤和夫, 上杉志成. 脂質生合成を抑制する内因性小分子化合物. 天然有機化合物討論会講演要旨集(Web). 2014. 56th. 85-89(J-STAGE)

ｍore...

Patents (3)：

Books (10)：

ケミカルバイオロジー化合物集~研究展開のヒント~
オーム社 2018
生細胞内で RNA を操る~RNA ツールと化合物による細胞機能の理解~
生命科学研究レター 2018
ビオチン化体を利用した生化学的標的タンパク質精製法
化学同人 2015
Affinity-based isolation of molecular targets of clinically used drugs
Case Studies in Chemical Biology 2014
生理活性物質による創薬標的同定のコツ
創薬研究のためのタンパク質・プロテオミクス解析, 別冊, 141-146 2010

ｍore...

Lectures and oral presentations (65)：

RNA hacking技術に基づいたXNA Stapleによるin vivo遺伝子発現抑制技術の開発
(日本核酸医薬学会第8回年会 2023)
生細胞内でRNAを操る
(日本核酸医薬学会第8回年会 2023)
生細胞内でRNA機能を操作して生命現象を理解する
(久留米工業高等専門学校生物応用化学科セミナー 2022)
Development of Novel Nucleic Acid Drug Technology Involving RNA Higher-Order Structural Changes
(Japanese Society for Chemical Biology 2022)
Gene expression regulation using Staple nucleic acids for the treatment of Parkinson's disease
(Japanese Society for Chemical Biology 2022)

ｍore...

Committee career (2)：

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page