Research keywords (1)：
RNA Biology, Oogenesis, Primordial follicles, Live imaging
Research theme for competitive and other funds (13)：
2023 - 2028 Dynamic reproductive lifespan: Life-long changes and fluctuations in germ cell function and risk for next generation
2020 - 2024 Regulatory mechanisms of primordial follicle activation mediated by RNA-binding proteins
2021 - 2023 In vivoライブイメージングで迫る原始卵胞の不均一性と活性化機構の理解
2020 - 2021 原始卵胞の維持に関わる細胞質RNP顆粒の機能解明
2019 - 2021 卵母細胞に顕在する新規細胞質顆粒が担う原始卵胞の品質管理機構
2019 - 2020 原始卵胞の活性化制御を担う新規細胞質顆粒の機能解明
2017 - 2020 Primordial follicle formation: insights from the study of RNA-binding proteins
2015 - 2018 Screening of essential ICB associate factors for spermatogenesis to understand male infertility
2013 - 2018 Establishment of sexual epigenome of germ cell via RNA-mediated mechanism
2016 - 2018 RNA結合タンパク質間の拮抗作用が介する原始卵胞の維持と活性化の制御機構
2014 - 2017 RNA-mediated regulatory mechanisms involved in germ cell development
2014 - 2016 RNA制御による原始卵胞維持機構の解明
2013 - 2015 Analyzes of RNA-binding proteins involved in sexual differentiation of male germ cells and oogenesis in mice
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Papers (18)：
Ryuki Shimada, Yuzuru Kato, Naoki Takeda, Sayoko Fujimura, Kei-ichiro Yasunaga, Shingo Usuki, Hitoshi Niwa, Kimi Araki, Kei-ichiro Ishiguro. STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nature Communications. 2023. 14. 1
Yuzuru Kato, Yumiko Saga. Antagonism between DDX6 and PI3K-AKT signaling is an oocyte-intrinsic mechanism controlling primordial follicle growth. Biology of reproduction. 2023
Hiroko Sano, Akira Nakamura, Mariko Yamane, Hitoshi Niwa, Takashi Nishimura, Kimi Araki, Kazumasa Takemoto, Kei-Ichiro Ishiguro, Hiroki Aoki, Yuzuru Kato, et al. The polyol pathway is an evolutionarily conserved system for sensing glucose uptake. PLoS biology. 2022. 20. 6. e3001678
Ryuki Shimada, Hiroko Koike, Takamasa Hirano, Yuzuru Kato, Yumiko Saga. NANOS2 suppresses the cell cycle by repressing mTORC1 activators in embryonic male germ cells. iScience. 2021. 24. 8. 102890-102890
Kurumi Fukuda, Masafumi Muraoka, Yuzuru Kato, Yumiko Saga. Decoding the transcriptome of pre-granulosa cells during the formation of primordial follicles in the mouse†. Biology of reproduction. 2021. 105. 1. 179-191
