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J-GLOBAL ID：201402200691311717   Reference number：14A0093018

Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P₁/S1P₃-dependent β-arrestin/c-Src pathways

スフィンゴシン-1-リン酸が誘導するFlk-1トランス活性化はS1P₁/S1P₃依存性β-アレスチン/c-Src経路を通じてマウス胚性幹細胞増殖を刺激する

Author (8)： RYU Jung Min (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...) ,  RYU Jung Min (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine, Chonnam National Univ., Gwangju 500-757, KOR) ,  BAEK Young Bin (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...) ,  SHIN Myung Sun (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...) ,  PARK Ji Hoon (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...) ,  PARK Soo Hyun (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine, Chonnam National Univ., Gwangju 500-757, KOR) ,  LEE Jang Hern (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...) ,  HAN Ho Jae (Dep. of Veterinary Physiology, Coll. of Veterinary Medicine and Res. Inst. for Veterinary Sci., Seoul National Univ. ...)
Material： Stem Cell Research (Web)  (Stem Cell Res (Web))
Volume： 12  Issue： 1  Page： 69-85  Publication year： Jan. 2014 
JST Material Number： U7041A  ISSN： 1873-5061  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： cytokine receptor ,  receptor tyrosine kinase ,  *ES cell ,  *Cell Proliferation ,  membrane receptor ,  ERK ,  JNK MAP kinase ,  Proteins ,  *phospholipid ,  Src protein ,  RT-PCR ,  Western blotting ,  fluorescent antibody technique ,  immunoprecipitation ,  subcellular distribution ,  density gradient centrifugation ,  flow cytometry ,  Cell Cycle ,  gene targetting ,  *Mouse Embryonic Stem Cells ,  Sphingosine-1-Phosphate Receptors ,  beta-arrestin ,  c-Src ,  co-immunoprecipitation ,  Signal Transduction ,  Vascular Endothelial Growth Factor Receptor-2 ,  Gene Knockdown Technique ,  bioassay ,  immunoassay
Semi thesaurus term： VEGF ,  cellular signal transduction ,  Flk 1 ,  gene knockdown

JST classification (2)： Cell physiology in general  (EF02010S) ,  Biological function  (EB05020M)

Substance index (1)： Sphingosine-1-phosphate

Terms in the title (11)： スフィンゴシン-1-リン酸 ,  誘導 ,  Flk-1 ,  トランス活性化 ,  依存性 ,  アレスチン ,  c-Src ,  経路 ,  マウス胚性幹細胞 ,  増殖 ,  刺激