Art

J-GLOBAL ID：201402202589060974   Reference number：14A1065030

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

ヒトにおける基底状態多能性へ向けた転写因子制御回路のリセット

Author (21)： TAKASHIMA Yasuhiro (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  TAKASHIMA Yasuhiro (PRESTO, Japan Sci. and Technol. Agency, 4-1-8 Honcho, Kawaguchi, Saitama, 332-0012, JPN) ,  GUO Ge (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  LOOS Remco (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  LOOS Remco (European Molecular Biology Lab., European Bioinformatics Inst., Wellcome Trust Genome Campus, Hinxton CB10 1SD, GBR) ,  NICHOLS Jennifer (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  NICHOLS Jennifer (Dep. of Physiology, Dev., and Neuroscience, Univ. of Cambridge, Tennis Court Road, Cambridge CB2 3EG, GBR) ,  FICZ Gabriella (Centre for Haemato-Oncology, Barts Cancer Inst., Univ. of London, Charterhouse Square, London EC1M 6BQ, GBR) ,  KRUEGER Felix (Babraham Inst., Babraham, CB22 3AT, GBR) ,  OXLEY David (Babraham Inst., Babraham, CB22 3AT, GBR) ,  SANTOS Fatima (Babraham Inst., Babraham, CB22 3AT, GBR) ,  CLARKE James (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  MANSFIELD William (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  REIK Wolf (Babraham Inst., Babraham, CB22 3AT, GBR) ,  REIK Wolf (Centre for Trophoblast Res., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 3EG, GBR) ,  REIK Wolf (Wellcome Trust Sanger Inst., Wellcome Trust Genome Campus, Hinxton CB10 1SA, GBR) ,  BERTONE Paul (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  BERTONE Paul (European Molecular Biology Lab., European Bioinformatics Inst., Wellcome Trust Genome Campus, Hinxton CB10 1SD, GBR) ,  BERTONE Paul (Genome Biology and Developmental Biology Units, European Molecular Biology Lab., Meyerhofstraβe 1, 69117 Heidelberg ...) ,  SMITH Austin (Wellcome Trust-Medical Res. Council Stem Cell Inst., Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1QR, GBR) ,  SMITH Austin (Dep. of Biochemistry, Univ. of Cambridge, Tennis Court Road, Cambridge CB2 1GA, GBR)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 158  Issue： 6  Page： 1254-1269  Publication year： Sep. 11, 2014 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,  *cultured cell ,  *stem cell ,  *ability ,  cell differentiation ,  transcription factor ,  *genetic regulation ,  gene ,  DNA binding protein ,  transformation ,  replication ,  cell physiology ,  metabolic regulation ,  gene rearrangement ,  *induced pluripotent stem cell
Semi thesaurus term： KLF2遺伝子 ,  KLF2 protein ,  Klf4 protein ,  Nanog gene ,  epigenetics regulation ,  mitochondrial activity ,  autoreproduction ,  *multipotency ,  *transcriptional regulation ,  transcriptional regulator ,  Cell Line

JST classification (3)： Cell physiology in general  (EF02010S) ,  Gene manipulation  (EC02050B) ,  Biological function  (EB03040U)

Terms in the title (5)： ヒト ,  基底状態 ,  多能性 ,  転写因子 ,  リセット