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J-GLOBAL ID：201402205231590016   Reference number：14A0935305

Microfluidic perfusion culture chip providing different strengths of shear stress for analysis of vascular endothelial function

血管内皮機能解析のための異なる強度のせん断応力を生じる灌流培養マイクロ流体チップ

Author (6)： HATTORI Koji (Res. Center for Stem Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol. (AIST), Central 5th ...) ,  MUNEHIRA Yoichi (Frontier Res. Laboratories, R&D Div., Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, JPN) ,  KOBAYASHI Hideki (Frontier Res. Laboratories, R&D Div., Daiichi Sankyo Co., Ltd., 1-2-58, Hiromachi, Shinagawa-ku, Tokyo 140-8710, JPN) ,  SATOH Taku (Res. Center for Stem Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol. (AIST), Central 5th ...) ,  SUGIURA Shinji (Res. Center for Stem Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol. (AIST), Central 5th ...) ,  KANAMORI Toshiyuki (Res. Center for Stem Cell Engineering, National Inst. of Advanced Industrial Sci. and Technol. (AIST), Central 5th ...)
Material： Journal of Bioscience and Bioengineering
Volume： 118  Issue： 3  Page： 327-332  Publication year： Sep. 2014 
JST Material Number： G0535B  ISSN： 1389-1723  CODEN： JBBIF6  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： chip ,...
Semi thesaurus term： *microfluidic chip ,...

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JST classification (2)： Cell and tissue culture methods  (EA03040R) ,  Function and strength analysis in living organisms  (EL03040Y)

Reference (35)：

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• Langille, B. L. and O'Donnell, E.: Reductions in arterial diameter produced by chronic decreases in blood flow are endothelium-dependent, Science, 231, 405-407 (1986).
• Devies, P. F. and Tripathi, S. C.: Mechanical stress mechanisms and the cell. An endothelial paradigm, Circ. Res., 72, 239-245 (1993).
• Devies, P. F.: Flow-mediated endothelial mechanotransduction, Physiol. Rev., 75, 519-560 (1995).
• Griffioen, A. W. and Molema, G.: Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation, Pharmacol. Rev., 52, 237-268 (2000).

Terms in the title (5)： 血管内皮機能 ,  解析 ,  せん断応力 ,  灌流培養 ,  マイクロ流体チップ