Art

J-GLOBAL ID：201402206874900450   Reference number：14A0269443

A disintegrin and metalloproteinase 17 (ADAM17) mediates epidermal growth factor receptor transactivation by angiotensin II on hepatic stellate cells

ジスインテグリンおよびメタロプロテイナーゼ17(ADAM17)は肝星状細胞でのアンジオテンシンIIによる上皮成長因子受容体トランス活性化を媒介する

Author (13)： OIKAWA Hiroki (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...) ,  MAESAWA Chihaya (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...) ,  MAESAWA Chihaya (Dep. of Tumor Biology, Inst. of Biomedical Sci., Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun ...) ,  TATEMICHI Yoshinori (Dep. of Internal Medicine, School of Medicine, Iwate Medical Univ., Uchimaru 19-1, Morioka, Iwate 020-8505, JPN) ,  NISHINARI Yutaka (Dep. of Tumor Biology, Inst. of Biomedical Sci., Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun ...) ,  NISHINARI Yutaka (Dep. of Surgery, School of Medicine, Iwate Medical Univ., Uchimaru 19-1, Morioka, Iwate 020-8505, JPN) ,  NISHIYA Masao (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...) ,  MIZUGAI Hisata (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...) ,  MIZUGAI Hisata (Dep. of Internal Medicine, School of Medicine, Iwate Medical Univ., Uchimaru 19-1, Morioka, Iwate 020-8505, JPN) ,  IKEDA Aya (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...) ,  OIKAWA Kanta (Dep. of Internal Medicine, School of Medicine, Iwate Medical Univ., Uchimaru 19-1, Morioka, Iwate 020-8505, JPN) ,  TAKIKAWA Yasuhiro (Dep. of Internal Medicine, School of Medicine, Iwate Medical Univ., Uchimaru 19-1, Morioka, Iwate 020-8505, JPN) ,  MASUDA Tomoyuki (Dep. of Pathology, School of Medicine, Iwate Medical Univ., 2-1-1 Nishitokuta, Yahaba-Cho, Shiwa-Gun, Iwate 028-3694 ...)
Material： Life Sciences  (Life Sciences including Pharmacology Letters)
Volume： 97  Issue： 2  Page： 137-144  Publication year： Mar. 03, 2014 
JST Material Number： B0699B  ISSN： 0024-3205  Document type： Article
Article type： 原著論文  Country of issue： Netherlands (NLD)  Language： ENGLISH (EN)

Thesaurus term： *matrix metalloproteinase ,  *toxic protein ,  *hepatocyte ,  *fibroblast ,  *Angiotensin II ,  EGF receptor ,  ELISA ,  angiotensin antagonist ,  *gene expression ,  EGF ,  glycoprotein ,  *hepatic fibrosis ,  *A Disintegrin And Metalloproteinase 17 ,  amphiregulin ,  *Disintegrins ,  *Trans-Activation (Genetics) ,  *Hepatic Stellate Cells ,  bioassay ,  *molecular genetic phenomenon
Semi thesaurus term： AT1 receptor antagonist ,  EGFR ,  *transactivation ,  *hepatic stellate cell ,  *hepatic fibrosis

JST classification (3)： Basic medicine on digestive system  (GH01020E) ,  Bioactive peptides  (EB08100U) ,  Liver  (EJ06060J)

Substance index (1)： TAPI-1

Terms in the title (7)： ジスインテグリン ,  メタロプロテイナーゼ ,  ADAM17 ,  肝星状細胞 ,  アンジオテンシンII ,  上皮成長因子受容体 ,  トランス活性化