Art

J-GLOBAL ID：201402208608576519   Reference number：14A0698431

TGF-β signal shifting between tumor suppression and fibro-carcinogenesis in human chronic liver diseases

ヒト慢性肝疾患における腫瘍抑制と線維-発癌の間のTGF-βシグナルシフト

Author (3)： MATSUZAKI Koichi (Kansai Medical Univ., Dep. of Gastroenterology and Hepatology, 10-15 Fumizonocho, 570-8506, Moriguchi, Osaka, JPN) ,  SEKI Toshihito (Kansai Medical Univ., Dep. of Gastroenterology and Hepatology, 10-15 Fumizonocho, 570-8506, Moriguchi, Osaka, JPN) ,  OKAZAKI Kazuichi (Kansai Medical Univ., Dep. of Gastroenterology and Hepatology, 10-15 Fumizonocho, 570-8506, Moriguchi, Osaka, JPN)
Material： Journal of Gastroenterology  (J Gastroenterol)
Volume： 49  Issue： 6  Page： 971-981  Publication year： Jun. 2014 
JST Material Number： Z0748A  ISSN： 0944-1174  Document type： Article
Article type： 文献レビュー  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： *cellular signal transduction ,...

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JST classification (3)： Tumors(=neoplasms)of digestive system  (GH04000D) ,  Carcinogenic mechanisms and factors  (GE02020C) ,  Cell physiology in general  (EF02010S)

Reference (88)：

• El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology. 2012;142:1264-73.
• Rehermann B, Nascimbeni M. Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol. 2005;5:215-29.
• Fattovich G, Bortolotti F, Donato F. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol. 2008;48:335-52.
• Tanaka Y, Kurbanov F, Mano S, et al. Molecular tracing of the global hepatitis C virus epidemic predicts regional patterns of hepatocellular carcinoma mortality. Gastroenterology. 2006;130:703-14.
• Friedman SL. Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol. 2010;7:425-36.

Terms in the title (7)： ヒト ,  慢性肝疾患 ,  腫瘍抑制 ,  発癌 ,  TGF-β ,  シグナル ,  シフト