Art

J-GLOBAL ID：201402211103427544   Reference number：14A1396554

Mutagenesis of the Novel Hericium erinaceus Ribonuclease, RNase He1, Reveals Critical Responsible Residues for Enzyme Stability and Activity

Hericium erinaceus由来新規リボヌクレアーゼRNアーゼHe1の変異誘発により酵素安定性及び酵素活性に寄与する重要残基を明らかにする

Author (4)： KOBAYASHI Hiroko (School of Pharmacy, Nihon Univ.) ,  MOTOYOSHI Naomi (School of Pharmacy, Nihon Univ.) ,  ITAGAKI Tadashi (School of Pharmacy, Nihon Univ.) ,  INOKUCHI Norio (School of Pharmacy, Nihon Univ.)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 11  Page： 1843-1847 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 短報  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human ,...
Semi thesaurus term： Aphyllophorales ,...

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JST classification (3)： Basic oncology in general  (GE02010R) ,  Enzyme in general  (EB09010D) ,  Microorganism biochemistry  (EG03020N)

Reference (17)：

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• 3) Kamiya Y, Oyama F, Oyama R, Sakakibara F, Nitta K, Kawauchi H, Takayanagi Y, Titani K. Amino Acid Sequence of a Lectin from Japanese Frog (Rana japonica) Eggs. J. Biochem., 108, 139-143 (1990).
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• 5) Fang EF, Zhang CZ, Fong WP, Ng TB. RNase MC2: a new Momordica charantia ribonuclease that induces apoptosis in breast cancer cells associated with activation of MAPKs and induction of caspase pathways. Apoptosis, 17, 377-387 (2012).

Terms in the title (7)： Hericium ,  リボヌクレアーゼ ,  RNアーゼ ,  変異誘発 ,  酵素安定性 ,  酵素活性 ,  残基