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J-GLOBAL ID：201402213039371656   Reference number：14A0775224

Antimutagenicity Screening of Extracts from Medicinal and Edible Plants against N-Methyl-N-nitrosourea by the Ames Assay

Ames試験によるN-メチル-N-ニトロソ尿素に対する薬用植物および食用植物抽出物の抗変異原性スクリーニング

Author (10)： TATSUZAKI Jin (Tokiwa Phytochemical Co. Ltd) ,  JINWEI Yang (Tokiwa Phytochemical Co. Ltd) ,  KOJO Yukiko (Kyoritsu Univ. of Pharmacy) ,  MINE Yusuke (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci.) ,  ISHIKAWA Satoko (Kyoritsu Univ. of Pharmacy) ,  ISHIKAWA Satoko (Fac. of Pharmacy, Keio Univ.) ,  MOCHIZUKI Masataka (Kyoritsu Univ. of Pharmacy) ,  MOCHIZUKI Masataka (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci.) ,  INAMI Keiko (Kyoritsu Univ. of Pharmacy) ,  INAMI Keiko (Fac. of Pharmaceutical Sciences, Tokyo Univ. of Sci.)
Material： Genes and Environment  (Genes Environ)
Volume： 36  Issue： 2  Page： 39-46 (J-STAGE)  Publication year： 2014 
JST Material Number： X0839A  ISSN： 1880-7046  CODEN： GEENGP  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： Ames test ,...
Semi thesaurus term： Glycyrrhiza aspera

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JST classification (1)： Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (1)： Methylnitrosourea

Reference (67)：

• 1 Lijinsky W. Chemistry and biology of N-nitroso compounds. Cambridge Monographs on Cancer Research. Cambridge: Cambridge University Press; 1992.
• 2 Tricker AR. N-Nitroso compounds and man: sources of exposure, endogenous formation and occurrence in body fluids. Eur J Cancer Prev. 1997; 6: 226-68.
• 3 Crews C. The determination of <i>N</i>-nitrosamines in food. Quality Assurance and Safety of Crops & Foods. 2010; 2: 2-12.
• 4 Nair J, Ohshima H, Nair UJ, Bartsch H. Endogenous formation of nitrosamine es and oxidative DNA-damaging agents in tobacco users. Crit Rev Toxicol. 1996; 26: 149-61.
• 5 Iavicoli I, Carelli G. Evaluation of occupational exposure to N-nitrosamines in a rubber-manufacturing industry. J Occup Environ Med. 2006; 48: 195-8.

Terms in the title (7)： Ames試験 ,  N-メチル-N-ニトロソ尿素 ,  薬用植物 ,  食用植物 ,  抽出物 ,  抗変異原性 ,  スクリーニング