Art

J-GLOBAL ID：201402222366881837   Reference number：14A0357627

Prion-like Polymerization Underlies Signal Transduction in Antiviral Immune Defense and Inflammasome Activation

プリオン様の重合が抗ウイルス性免疫防御およびインフラマソーム活性化におけるシグナル伝達の基礎をなす

Author (9)： CAI Xin (Dep. of Molecular Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  CHEN Jueqi (Dep. of Molecular Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  XU Hui (Dep. of Molecular Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  XU Hui (Dep. of Cell Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  LIU Siqi (Dep. of Molecular Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  JIANG Qiu-xing (Dep. of Cell Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  HALFMANN Randal (Dep. of Biochemistry, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  CHEN Zhijian J. (Dep. of Molecular Biology, Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA) ,  CHEN Zhijian J. (Howard Hughes Medical Inst., Univ. of Texas Southwestern Medical Center, Dallas, TX 75390, USA)
Material： Cell (Cambridge, Mass.)  (Cell (Camb. Mass.))
Volume： 156  Issue： 6  Page： 1207-1222  Publication year： Mar. 13, 2014 
JST Material Number： A0707B  ISSN： 0092-8674  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： cultured cell ,  human ,  *protein complex ,  *natural immunity ,  Proteins ,  adaptor protein ,  caspase ,  bacterial protein ,  signal transduction receptor ,  set ,  ASC ,  CARD Signaling Adaptor Proteins ,  *Inflammasomes ,  Caspase 1 ,  pilin ,  Inflammation reaction ,  *Intracellular signaling ,  protein assembly ,  immune response ,  *Signal Transduction ,  nod-like receptor protein 3 ,  Cell Line
Semi thesaurus term： immunological reaction ,  *cellular signal transduction ,  NLRP3 ,  正常プリオン ,  Cell Line

JST classification (2)： Biological function  (EB03040U) ,  Cell physiology in general  (EF02010S)

Terms in the title (8)： プリオン ,  重合 ,  抗ウイルス性 ,  免疫防御 ,  インフラマソーム ,  活性化 ,  シグナル伝達 ,  基礎