Art

J-GLOBAL ID：201402225334202732   Reference number：14A0552350

Synthesis of 1-(4-Aminobutyl)-2-iminoimidazolidin-4-one Aimed at Preparation of a Creatinine-Specific Antibody

クレアチニン特異抗体の調製を目的とした1-(4-アミノブチル)-2-イミノイミダゾリジン-4-オンの合成

Author (8)： MORIYA Shun-suke (Translational Medical Res. Center, Tokyo Metropolitan Inst. of Medical Sci.) ,  TERAYAMA Naoki (Dep. of Applied Chemistry, Kogakuin Univ.) ,  HIRAMATSU Kyoko (Translational Medical Res. Center, Tokyo Metropolitan Inst. of Medical Sci.) ,  KAWAKITA Masao (Translational Medical Res. Center, Tokyo Metropolitan Inst. of Medical Sci.) ,  KIRYU Tatsuya (Dep. of Applied Chemistry, Kogakuin Univ.) ,  KAWANISHI Takato (Dep. of Applied Chemistry, Kogakuin Univ.) ,  YASUI Eiko (Dep. of Applied Chemistry, Kogakuin Univ.) ,  NAGUMO Shinji (Dep. of Applied Chemistry, Kogakuin Univ.)
Material： Chemical and Pharmaceutical Bulletin  (Chemical & Pharmaceutical Bulletin)
Volume： 62  Issue： 4  Page： 350-353 (J-STAGE)  Publication year： 2014 
JST Material Number： G0504A  ISSN： 0009-2363  CODEN： CPBTAL  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *antibody ,...
Semi thesaurus term： hare ,...

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JST classification (1)： Antigens,antibodies,complements in general  (ED04010A)

Substance index (9)： [4-(tert-Butyldimethylsilyloxy)butylamino]acetic acid tert-butyl ester ,  1-(4-Aminobutyl)-2-iminoimidazolidine-4-one ,  2-(Benzyloxycarbonylimino)-3-(benzyloxycarbonyl)-2,3,4,5,6,7-hexahydro-1H-1,3-diazepine-1-acetic acid tert-butyl ester ,  4-Benzylamino-1-butanol ,  N-(4-Azidobutyl)-N-[(benzyloxycarbonylamino)(benzyloxycarbonylimino)methyl]glycine tert-butyl ester ,  N-(4-Hydroxybutyl)-N-[(benzyloxycarbonylamino)(benzyloxycarbonylimino)methyl]glycine tert-butyl ester ,  N-[4-(tert-Butyldimethylsilyloxy)butyl]-N-[(benzyloxycarbonylamino)(benzyloxycarbonylimino)methyl]glycine tert-butyl ester ,  Creatinine ,  Benzyl(4-hydroxybutyl)aminoacetic acid tert-butyl ester

Reference (15)：

• 1) Moriya S., Hiramatsu K., Kimura E., Matsumoto K., Kawakita M., J. Clin. Lab. Anal., in press. 10.1002/jcla.21709
• 2) Hiramatsu K., Takahashi K., Yamaguchi T., Matsumoto H., Miyamoto H., Tanaka S., Tanaka C., Tamamori Y., Imajo M., Kawaguchi M., Toi M., Mori T., Kawakita M., Clin. Cancer Res., 11, 2986-2990 (2005).
• 3) Kawakita M., Hiramatsu K., J. Biochem., 139, 315-322 (2006).
• 4) Hiramatsu K., Sakaguchi K., Fujie N., Saitoh F., Takahama E., Moriya S., Iwasaki K., Sakaguchi M., Takahashi K., Kawakita M., Ann. Clin. Biochem., in press.
• 5) Yaffé M., Z. Phys. Chem., 10, 391-400 (1886).

Terms in the title (3)： クレアチニン ,  特異抗体 ,  調製