The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

NISHITSUJI Kazuchika; TOMIYAMA Takami; ISHIBASHI Kenichi; ITO Kazuhiro; TERAOKA Rie; LAMBERT Mary P.; KLEIN William L.; MORI Hiroshi

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J-GLOBAL ID：201402227852470930 Reference number：14A0001482

The E693Δ Mutation in Amyloid Precursor Protein Increases Intracellular Accumulation of Amyloid β Oligomers and Causes Endoplasmic Reticulum Stress-Induced Apoptosis in Cultured Cells

アミロイド前駆体タンパク質におけるE693Δ変異はアミロイドβオリゴマーの細胞内蓄積を増加させ,培養細胞における小胞体ストレス反応誘発性アポトーシスを引き起こす

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Volume： 174 Issue： 3 Page： 957-969 Publication year： Mar. 2009
JST Material Number： E0065B ISSN： 0002-9440 CODEN： AJPAA Document type： Article
Country of issue： Netherlands (NLD) Language： ENGLISH (EN)

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