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J-GLOBAL ID：201402230408422326   Reference number：14A0166375

Cysteine string protein 1 (CSP1) modulates insulin sensitivity by attenuating glucose transporter 4 (GLUT4) vesicle docking with the plasma membrane

システインストリング蛋白質1(CSP1)はグルコース輸送体4(GLUT4)小胞の形質膜との結合を減弱させることによりインシュリン感受性を調節する

Author (17)： JAMBALDORJ Bayasgalan (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  TERADA Eri (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  HOSAKA Toshio (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  KISHUKU Yuka (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  TOMIOKA Yukiko (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  IWASHIMA Kaori (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  HIRATA Yohko (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  TESHIGAWARA Kiyoshi (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  THI KIM LE Chung (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  NAKAGAWA Tadahiko (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  HARADA Nagakatsu (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  SAKAI Tohru (Dep. of Public Health and Applied Nutrition, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  SAKAUE Hiroshi (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  MATSUMOTO Toshio (Dep. of Medicine and Bioregulatory Sciences, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  FUNAKI Makoto (Clinical Res. Center for Diabetes, Tokushima Univ. Hospital) ,  TAKAHASHI Akira (Dep. of Preventive Environment and Nutrition, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School) ,  NAKAYA Yutaka (Dep. of Nutrition and Metabolism, Inst. of Health Biosciences, the Univ. of Tokushima Graduate School)
Material： Journal of Medical Investigation  (JMI)
Volume： 60  Issue： 3.4  Page： 197-204 (J-STAGE)  Publication year： 2013 
JST Material Number： G0657A  ISSN： 1343-1420  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： fat cell ,...
Semi thesaurus term： *insulin resistance ,...

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JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Reference (25)：

• 1. Larance M, Ramm G, James DE: The GLUT4 code. Mol Endocrinol 22: 226-233, 2008
• 2. Sollner TH: Regulated exocytosis and SNARE function (Review). Mol Membr Biol 20: 209-220, 2003
• 3. Foster LJ, Klip A: Mechanism and regulation of GLUT-4 vesicle fusion in muscle and fat cells. Am J Physiol Cell Physiol 279: C877-890, 2000
• 4. Watson RT, Kanzaki M, Pessin JE: Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr Rev 25: 177-204, 2004
• 5. Evans G J, Morgan A, Burgoyne RD: Tying everything together: the multiple roles of cysteine string protein (CSP) in regulated exocytosis. Traffic 4: 653-659, 2003

Terms in the title (8)： 蛋白質 ,  グルコース輸送体4 ,  GLUT4 ,  小胞 ,  形質膜 ,  減弱 ,  インシュリン感受性 ,  調節