Art

J-GLOBAL ID：201402234383585867   Reference number：14A0812001

Chronic variable stress activates hematopoietic stem cells

動脈硬化:慢性的な種々のストレスは造血幹細胞を活性化する

Author (16)： HEIDT Timo (Harvard Medical School, Massachusetts, USA) ,  SAGER Hendrik B (Harvard Medical School, Massachusetts, USA) ,  COURTIES Gabriel (Harvard Medical School, Massachusetts, USA) ,  DUTTA Partha (Harvard Medical School, Massachusetts, USA) ,  IWAMOTO Yoshiko (Harvard Medical School, Massachusetts, USA) ,  ZALTSMAN Alex (Harvard Medical School, Massachusetts, USA) ,  LIN Charles P (Harvard Medical School, Massachusetts, USA) ,  VINEGONI Claudio (Harvard Medical School, Massachusetts, USA) ,  SWIRSKI Filip K (Harvard Medical School, Massachusetts, USA) ,  WEISSLEDER Ralph (Harvard Medical School, Massachusetts, USA) ,  NAHRENDORF Matthias (Harvard Medical School, Massachusetts, USA) ,  VON ZUR MUHLEN Constantin (Univ. Heart Center, Freiburg, DEU) ,  BODE Christoph (Univ. Heart Center, Freiburg, DEU) ,  FRICCHIONE Gregory L (Massachusetts General Hospital, Massachusetts, USA) ,  DENNINGER John (Massachusetts General Hospital, Massachusetts, USA) ,  LIBBY Peter (Brigham and Women’s Hospital, Massachusetts, USA)
Material： Nature Medicine  (Nat Med)
Volume： 20  Issue： 7  Page： 754-758  Publication year： Jul. 2014 
JST Material Number： W0636A  ISSN： 1078-8956  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： hematopoietic stem cell ,  *activation ,  *emotional stress ,  *atherosclerosis ,  risk factor ,  metabasis ,  *cellular signal transduction ,  brain ,  immunity ,  hypothalamus ,  pituitary gland ,  adrenal gland ,  adrenal medulla ,  sympathetic nerve system ,  catecholamine ,  *stress(physiology) ,  *cell proliferation ,  pharmacological action ,  leukocytosis ,  monocyte ,  mouse(animal) ,  neurotransmitter ,  environment ,  *apo E ,  aminoalcohol ,  primary amine ,  secondary alcohol ,  polyol
Semi thesaurus term： *cell activation ,  *psychosocial stress ,  Disease Progression ,  Crisis ,  *Cross-Talk ,  Immune System ,  Hypothalamo-hypophysial-adrenal axis ,  *chronic stress ,  cell proliferation promoting effect ,  Neutrophilia ,  Stem Cell Niche

JST classification (2)： Basic medicine on cardiovascular system  (GJ01020K) ,  Cell physiology in general  (EF02010S)

Substance index (1)： Norepinephrine

Terms in the title (5)： 動脈硬化 ,  慢性 ,  ストレス ,  造血幹細胞 ,  活性化