Art

J-GLOBAL ID：201402236188312247   Reference number：14A0006530

Targeting Plasmodium PI(4)K to eliminate malaria

マラリア根絶のためにマラリア原虫のPI(4)Kを標的とする

Author (40)： MCNAMARA Case W. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  ROLAND Jason (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  NAGLE Advait (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  CHATTERJEE Arnab K. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  MCCORMACK Susan L. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  GAGARING Kerstin (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  IBANEZ Maureen (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  KATO Nobutaka (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  KUHEN Kelli L. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  PLOUFFE David M. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  BURSULAYA Badry (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  TULLY David C. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  GLYNNE Richard J. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  WINZELER Elizabeth A. (Genomics Inst. of the Novartis Res. Foundation, California, USA) ,  LEE Marcus C. S. (Columbia Univ. Medical Center, New York, USA) ,  KUMAR T. R. Santha (Columbia Univ. Medical Center, New York, USA) ,  HENRICH Philipp P. (Columbia Univ. Medical Center, New York, USA) ,  FIDOCK David A. (Columbia Univ. Medical Center, New York, USA) ,  LIM Chek Shik (Novartis Inst. for Tropical Disease, Singapore) ,  LIM Siau Hoi (Novartis Inst. for Tropical Disease, Singapore) ,  SIMON Oliver (Novartis Inst. for Tropical Disease, Singapore) ,  YEUNG Bryan K. S. (Novartis Inst. for Tropical Disease, Singapore) ,  BODENREIDER Christophe (Novartis Inst. for Tropical Disease, Singapore) ,  DIAGANA Thierry T. (Novartis Inst. for Tropical Disease, Singapore) ,  MANARY Micah J. (Univ. California, San Diego, California, USA) ,  MEISTER Stephan (Univ. California, San Diego, California, USA) ,  WINZELER Elizabeth A. (Univ. California, San Diego, California, USA) ,  ZEEMAN Anne-Marie (Biomedical Primate Res. Centre, Rijswijk, NLD) ,  KOCKEN Clemens H. M. (Biomedical Primate Res. Centre, Rijswijk, NLD) ,  DECHERING Koen J. (TropIQ Health Sci., Nijmegen, NLD) ,  TIMMERMAN Martijn (TropIQ Health Sci., Nijmegen, NLD) ,  SAUERWEIN Robert W. (TropIQ Health Sci., Nijmegen, NLD) ,  FISCHLI Christoph (Swiss Tropical and Public Health Inst., Basel, CHE) ,  ROTTMANN Matthias (Swiss Tropical and Public Health Inst., Basel, CHE) ,  ROTTMANN Matthias (Univ. Basel, Basel, CHE) ,  RAMEH Lucia (Boston Univ., Massachusetts, USA) ,  TRAPPE Joerg (Novartis Inst. for BioMedical Res., Basel, CHE) ,  HAASEN Dorothea (Novartis Inst. for BioMedical Res., Basel, CHE) ,  SAUERWEIN Robert W. (Radboud Univ., Nijmegen, NLD) ,  SUWANARUSK Rossarin (Agency for Sci. Technol. and Res. (A*STAR), Singapore)
Material： Nature (London)  (Nature (Lond))
Volume： 504  Issue： 7479  Page： 248-253  Publication year： Dec. 12, 2013 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： Malaria ,  *phosphatidylinositol 4-kinase ,  Plasmodium falciparum ,  subcellular distribution ,  phosphatidylinositol ,  life cycle ,  antiprotozoal action ,  target ,  Plasmodium cynomolgi ,  Phosphatidylinositol 4-Phosphates ,  anti-malarial activity ,  *Plasmodium ,  Plasmodium vivax ,  *Drug target ,  *microorganism ,  *protozoa ,  *Sporozoa
Semi thesaurus term： *Plasmodium ,  Plasmodium vivax ,  *Drug target

JST classification (1)： Basic research of antiprotozoan drugs and anthelmintics  (GW17080G)

Terms in the title (4)： マラリア ,  マラリア原虫 ,  pI ,  標的