Art

J-GLOBAL ID：201402240932055743   Reference number：14A0618600

Protective Effects of Fluvoxamine against Ischemia/Reperfusion Injury in Isolated, Perfused Guinea-Pig Hearts

分離,灌流されたモルモット心臓の虚血/再灌流障害に対するフルボキサミンの保護作用

Author (15)： MUTO Tatsuya (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  MUTO Tatsuya (Meitetsu Hospital Pharmacy) ,  USUDA Haruki (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  YAMAMURA Aya (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  YOSHIDA Koji (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  OHASHI Ai (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  MITSUI-SAITOH Kumiko (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  MITSUI-SAITOH Kumiko (Fac. of Sports and Health Sci., Nagoya Gakuin Univ.) ,  SAKAI Junichi (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  SAKAI Junichi (Fac. of Sports and Health Sci., Nagoya Gakuin Univ.) ,  SUGIMOTO Yumi (Lab. of Pharmacology, Dep. of Clinical Pharmacy, Yokohama Coll. of Pharmacy) ,  MIZUTANI Hideki (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  NONOGAKI Tsunemasa (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  HOTTA Yoshihiro (Coll. of Pharmacy, Kinjo Gakuin Univ.) ,  HOTTA Yoshihiro (Dep. of Pharmacology, Aichi Medical Univ. School of Medicine)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 5  Page： 731-739 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： guinea pig ,...
Semi thesaurus term： ischemia-reperfusion injury ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0618600&from=J-GLOBAL&jstjournalNo=S0989A") }}

JST classification (1)： Basic research of cardioactive drugs  (GW07020N)

Substance index (1)： Fluvoxamine

Reference (43)：

• 1) Frishman WH, Grewall P. Serotonin and the heart. Ann. Med., 32, 195-209 (2000).
• 2) Villalón CM, Heiligers JP, Centurión D, De Vries P, Saxena PR. Characterization of putative 5-HT₇ receptors mediating tachycardia in the cat. Br. J. Pharmacol., 121, 1187-1195 (1997).
• 3) Brogden RN, Sorkin EM. Ketanserin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in hypertension and peripheral vascular disease. Drugs, 40, 903-949 (1990).
• 4) Grover GJ, Sargent CA, Dzwonczyk S, Normandin DE, Antonaccio MJ. Protective effect of serotonin (5-HT₂) receptor antagonists in ischemic rat hearts. J. Cardiovasc. Pharmacol., 22, 664-672 (1993).
• 5) Grover GJ, Parham CS, Youssef S, Ogletree ML. Protective effect of the serotonin receptor antagonist cinanserin in two canine models of pacing-induced myocardial ischemia. Pharmacology, 50, 286-297 (1995).

Terms in the title (7)： 灌流 ,  モルモット ,  心臓 ,  虚血 ,  再灌流障害 ,  フルボキサミン ,  保護作用