Art

J-GLOBAL ID：201402246583608673   Reference number：14A0393065

An Easy-to-use Genotoxicity Assay Using EGFP-MDC1-expressing Human Cells

EGFP-MDC1発現ヒト細胞を用いる簡単な遺伝子毒性試験

Author (7)： MATSUDA Shun (Res. Center for Environmental Quality Management, Kyoto Univ.) ,  MATSUDA Ryo (Radiation Biology Center, Kyoto Univ.) ,  MATSUDA Yoko (Res. Center for Environmental Quality Management, Kyoto Univ.) ,  YANAGISAWA Shin-ya (Res. Center for Environmental Quality Management, Kyoto Univ.) ,  IKURA Masae (Radiation Biology Center, Kyoto Univ.) ,  IKURA Tsuyoshi (Radiation Biology Center, Kyoto Univ.) ,  MATSUDA Tomonari (Res. Center for Environmental Quality Management, Kyoto Univ.)
Material： Genes and Environment  (Genes Environ)
Volume： 36  Issue： 1  Page： 17-28 (J-STAGE)  Publication year： 2014 
JST Material Number： X0839A  ISSN： 1880-7046  CODEN： GEENGP  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *chromoprotein ,...
Semi thesaurus term： *Enhanced green fluorescence protein ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0393065&from=J-GLOBAL&jstjournalNo=X0839A") }}

JST classification (1)： Toxicity of chemical substances in general  (GZ02010C)

Reference (92)：

• 1 Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem. 1998; 273: 5858-68.
• 2 Rogakou EP, Boon C, Redon C, Bonner WM. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J Cell Biol. 1999; 146: 905-16.
• 3 Rothkamm K, Lobrich M. Evidence for a lack of DNA double-strand break repair in human cells exposed to very low x-ray doses. Proc Natl Acad Sci USA. 2003; 100: 5057-62.
• 4 Banath JP, Olive PL. Expression of phosphorylated histone H2AX as a surrogate of cell killing by drugs that create DNA double-strand breaks. Cancer Res. 2003; 63: 4347-50.
• 5 Elmroth K, Nygren J, Martensson S, Ismail IH, Hammarsten O. Cleavage of cellular DNA by calicheamicin gamma1. DNA Repair (Amst). 2003; 2: 363-74.

Terms in the title (6)： EGFP ,  MDC1 ,  発現 ,  ヒト ,  細胞 ,  遺伝子毒性試験