Art

J-GLOBAL ID：201402253795328731   Reference number：14A0552446

Macrophage Recognition of Toxic Advanced Glycosylation End Products through the Macrophage Surface-Receptor Nucleolin

マクロファージ表面受容体ヌクレオリンを介した毒性終末糖化産物のマクロファージ認識

Author (6)： MIKI Yuichi (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  DAMBARA Hikaru (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  TACHIBANA Yoshihiro (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  HIRANO Kazuya (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  KONISHI Mio (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences) ,  BEPPU Masatoshi (School of Pharmacy, Tokyo Univ. of Pharmacy and Life Sciences)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 4  Page： 588-596 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *glycoprotein ,...
Semi thesaurus term： *advanced glycation end products ,...

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JST classification (2)： Cell physiology in general  (EF02010S) ,  Receptors on cell membrane  (EF04030C)

Substance index (2)： Glyceraldehyde ,  Glycolaldehyde

Reference (49)：

• 1) Brownlee M, Vlassara H, Cerami A. Nonenzymatic glycosylation and the pathogenesis of diabetic complications. Ann. Intern. Med., 101, 527-537 (1984).
• 2) Takata K, Horiuchi S, Araki N, Shiga M, Saitoh M, Morino Y. Scavenger receptor of human monocytic leukemia cell line (THP-1) and murine macrophages for nonenzymatically glycosylated proteins. Biochim. Biophys. Acta, 986, 18-26 (1989).
• 3) Takata K, Horiuchi S, Araki N, Shiga M, Saitoh M, Morino Y. Endocytic uptake of nonenzymatically glycosylated proteins is mediated by a scavenger receptor for aldehyde-modified proteins. J. Biol. Chem., 263, 14819-14825 (1988).
• 4) Takeuchi M, Yanase Y, Matsuura N, Yamagishi Si S, Kameda Y, Bucala R, Makita Z. Immunological detection of a novel advanced glycation end-product. Mol. Med., 7, 783-791 (2001).
• 5) Hamada Y, Araki N, Koh N, Nakamura J, Horiuchi S, Hotta N. Rapid formation of advanced glycation end products by intermediate metabolites of glycolytic pathway and polyol pathway. Biochem. Biophys. Res. Commun., 228, 539-543 (1996).

Terms in the title (5)： マクロファージ ,  受容体 ,  ヌクレオリン ,  毒性 ,  終末糖化産物