Art

J-GLOBAL ID：201402268604095047   Reference number：14A1289457

A Noninvasive Metabolic Syndrome Model Using an Extremely Small Minipig, the Microminipig

極めて小さなミニブタ(マイクロミニピッグ)を用いた非侵襲的メタボリックシンドロームモデル

Author (17)： YAMAGUCHI Takehiro (Dep. of Cardiovascular Medicine, Osaka City Univ. Medical School, JPN) ,  YAMAZAKI Takanori (Dep. of Cardiovascular Medicine, Osaka City Univ. Medical School, JPN) ,  KAWAGUCHI Hiroaki (Lab. of Veterinary Histopathology, Joint Fac. of Veterinary Medicine, Kagoshima Univ., JPN) ,  TAWA Masashi (Dep. of Pharmacology, Shiga Univ. of Medical Sciences, JPN) ,  NAKAMURA Yasuhiro (Dep. of Cardiovascular Medicine, Osaka City Univ. Medical School, JPN) ,  NAKAMURA Yasuhiro (Dep. of Cardiology, Izumi Municipal Hospital, JPN) ,  SHIOTA Masayuki (Dep. of Pharmacology, Osaka City Univ. Medical School, JPN) ,  OSADA-OKA Mayuko (Dep. of Pharmacology, Osaka City Univ. Medical School, JPN) ,  OSADA-OKA Mayuko (Food Hygiene and Environmental Health Div. of Applied Life Sci., Kyoto Prefectural Univ., JPN) ,  TANIMOTO Akihide (Dep. of Molecular and Cellular Pathology, Kagoshima Univ. Graduate School of Medical and Dental Sciences, JPN) ,  OKAMURA Tomio (Dep. of Pharmacology, Shiga Univ. of Medical Sciences, JPN) ,  MIURA Katsuyuki (Dep. of Pharmacology, Osaka City Univ. Medical School, JPN) ,  MIURA Katsuyuki (Applied Pharmacology and Therapeutics, Osaka City Univ. Medical School, JPN) ,  IWAO Hiroshi (Dep. of Pharmacology, Osaka City Univ. Medical School, JPN) ,  IWAO Hiroshi (Dep. of Education, Shitennoji Univ., JPN) ,  YOSHIYAMA Minoru (Dep. of Cardiovascular Medicine, Osaka City Univ. Medical School, JPN) ,  IZUMI Yasukatsu (Dep. of Pharmacology, Osaka City Univ. Medical School, JPN)
Material： Journal of Pharmacological Sciences  (J Pharmacol Sci)
Volume： 126  Issue： 2  Page： 168-171 (J-STAGE)  Publication year： 2014 
JST Material Number： G0813A  ISSN： 1347-8613  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： miniature pig ,...
Semi thesaurus term： *マイクロミニピッグ ,...

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JST classification (1)： Metabolic diseases,nutritional diseases in general.  (GD05010J)

Substance index (1)： L-NAME

Reference (10)：

• 1 Washio M, Sasazuki S, Kodama H, Yoshimasu PK, Liu Y, Tanaka K, et al. Role of hypertension, dyslipidemia and diabetes mellitus in the development of coronary atherosclerosis in Japan. Jpn Circ J. 2001;65:731-737.
• 2 Jawien J. The role of an experimental model of atherosclerosis: apoE-knockout mice in developing new drugs against atherogenesis. Curr Pharm Biotechnol. 2012;13:2435-2439.
• 3 Bilheimer DW, Watanabe Y, Kita T. Impaired receptor-mediated catabolism of low density lipoprotein in the WHHL rabbit, an animal model of familial hypercholesterolemia. Proc Natl Acad Sci U S A. 1982;79:3305-3309.
• 4 Forster R, Ancian P, Fredholm M, Simianer H, Whitelaw B; Steering Group of the RP. The minipig as a platform for new technologies in toxicology. J Pharmacol Toxicol Methods. 2010;62:227-235.
• 5 Kaneko N, Itoh K, Sugiyama A, Izumi Y. Microminipig, a non-rodent experimental animal optimized for life science research: preface. J Pharmacol Sci. 2011;115:112-114.

Terms in the title (5)： ミニブタ ,  マイクロミニピッグ ,  非侵襲的 ,  メタボリックシンドローム ,  モデル