Art

J-GLOBAL ID：201402269544578430   Reference number：14A0414505

Complete response induced by half dose of sorafenib administration in advanced hepatocellular carcinoma with peritoneal dissemination

半量のソラフェニブにより完全奏効が得られた肝細胞癌腹膜播種の1例

Author (9)： MORIMOTO NAOKI (自治医科大学消化器・肝臓内科) ,  ISODA NORIO (自治医科大学消化器・肝臓内科) ,  OTAKE TOSHIYA (自治医科大学消化器・肝臓内科) ,  WATANABE SHUNJI (自治医科大学消化器・肝臓内科) ,  TSUKUI MAMIKO (自治医科大学消化器・肝臓内科) ,  MIYATA NATSUMI (自治医科大学消化器・肝臓内科) ,  HIROSAWA TAKUYA (自治医科大学消化器・肝臓内科) ,  NAGAMINE NOBUHIKO (自治医科大学消化器・肝臓内科) ,  SUGANO KENTARO (自治医科大学消化器・肝臓内科)
Material： 肝臓  (Acta Hepatologica Japonica)
Volume： 55  Issue： 2  Page： 100-105 (J-STAGE)  Publication year： 2014 
JST Material Number： Z0006B  ISSN： 0451-4203  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *antitumor drug ,...
Semi thesaurus term： 完全奏効 ,...

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JST classification (2)： Clinical application of antitumor(=antineoplastic)drugs  (GW16020L) ,  Drug therapy(=pharmacotherapy)for tumors  (GE03032C)

Substance index (1)： Sorafenib

Reference (33)：

• 1) Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008; 359: 378-390
• 2) Cheng AL, Kang YK, Chen Z, et al. Efficacy and safety of sorafenib in patients in the Asia-Pacific region with advanced hepatocellular carcinoma: a phase III randomised, double-blind, placebo-controlled trial. Lancet oncol 2009; 10: 25-34
• 3) Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-216
• 4) Llovet JM, Bruix J. Molecular targeted therapies in hepatocellular carcinoma. Hepatology 2008; 8: 1312-1327
• 5) Arii S, Sata M, Sakamoto M, et al. Management of hepatocellular carcinoma: Report of Consensus Meeting in the 45th Annual Meeting of the Japan Society of Hepatology (2009). Hepatol Res 2010; 40: 667-685

Terms in the title (3)： ソラフェニブ ,  肝細胞癌 ,  腹膜播種