Art

J-GLOBAL ID：201402273771336025   Reference number：14A0414489

Successful Telaprevir Treatment in Combination of Cyclosporine against Recurrence of Hepatitis C in the Japanese Liver Transplant Patients

日本人肝移植患者におけるC型肝炎の再発に対してシクロスポリンとの併用で成功したテラプレビル治療

Author (24)： KIKUCHI Mio (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  KIKUCHI Mio (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  OKUDA Yuki (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  UEDA Yoshihide (Dep. of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto Univ.) ,  NISHIOKA Yuki (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  UESUGI Miwa (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  HASHIMOTO Emina (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  TAKAHASHI Tamotsu (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  KAWAI Tomoki (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  HASHI Sachiyo (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  SHINKE Haruka (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  OMURA Tomohiro (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  OMURA Tomohiro (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  YONEZAWA Atsushi (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  YONEZAWA Atsushi (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  ITO Takashi (Div. of Hepatobiliary-Pancreatic Surgery and Transplantation, Dep. of Surgery, Graduate School of Medicine, Kyoto Univ.) ,  FUJIMOTO Yasuhiro (Div. of Hepatobiliary-Pancreatic Surgery and Transplantation, Dep. of Surgery, Graduate School of Medicine, Kyoto Univ.) ,  KAIDO Toshimi (Div. of Hepatobiliary-Pancreatic Surgery and Transplantation, Dep. of Surgery, Graduate School of Medicine, Kyoto Univ.) ,  CHIBA Tsutomu (Dep. of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto Univ.) ,  UEMOTO Shinji (Div. of Hepatobiliary-Pancreatic Surgery and Transplantation, Dep. of Surgery, Graduate School of Medicine, Kyoto Univ.) ,  MATSUBARA Kazuo (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  MATSUBARA Kazuo (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital) ,  MASUDA Satohiro (Dep. of Clinical Pharmacology and Therapeutics, Fac. of Medicine, Kyoto Univ. Hospital) ,  MASUDA Satohiro (Dep. of Pharmacy, Fac. of Medicine, Kyoto Univ. Hospital)
Material： Biological and Pharmaceutical Bulletin  (Biological & Pharmaceutical Bulletin)
Volume： 37  Issue： 3  Page： 417-423 (J-STAGE)  Publication year： 2014 
JST Material Number： S0989A  ISSN： 0918-6158  CODEN： BPBLEO  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： CYP3A4 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0414489&from=J-GLOBAL&jstjournalNo=S0989A") }}

JST classification (5)： Treatment for infectious diseases,parasitic diseases.  (GD01030D) ,  Drug therapy(=pharmacotherapy)for digestive system diseases  (GH05020G) ,  Clinical application of antiviral drugs  (GW17050Z) ,  Clinical application of immunotherapeutic agents and blood preparations  (GW22020O) ,  Interactions of drugs  (GV01070X)

Substance index (4)： Ciclosporin ,  Tacrolimus ,  Telaprevir ,  Ribavirin

Reference (31)：

• 1) Forestier N, Zeuzem S. Telaprevir for the treatment of hepatitis C. Expert Opin. Pharmacother., 13, 593-606 (2012).
• 2) Fowell AJ, Nash KL. Telaprevir: a new hope in the treatment of chronic hepatitis C? Adv. Ther., 27, 512-522 (2010).
• 3) Kim JJ, Culley CM, Mohammad RA. Telaprevir: an oral protease inhibitor for hepatitis C virus infection. Am. J. Health Syst. Pharm., 69, 19-33 (2012).
• 4) Kumada H, Toyota J, Okanoue T, Chayama K, Tsubouchi H, Hayashi N. Telaprevir with peginterferon and ribavirin for treatment-naive patients chronically infected with HCV of genotype 1 in Japan. J. Hepatol., 56, 78-84 (2012).
• 5) Wilby KJ, Greanya ED, Ford JA, Yoshida EM, Partovi N. A review of drug interactions with boceprevir and telaprevir: implications for HIV and transplant patients. Ann. Hepatol., 11, 179-185 (2012).

Terms in the title (10)： 日本人 ,  肝移植 ,  患者 ,  C型肝炎 ,  再発 ,  シクロスポリン ,  併用 ,  成功 ,  テラプレビル ,  治療