Art

J-GLOBAL ID：201402278376377652   Reference number：14A0572418

Curcumin targets the AKT-mTOR pathway for uterine leiomyosarcoma tumor growth suppression

クルクミンは子宮平滑筋肉腫の腫瘍増殖抑制のためにAKT-mTOR経路を標的とする

Author (8)： WONG Tze Fang (Tohoku Univ., Miyagi, JPN) ,  TAKEDA Takashi (Tohoku Univ., Miyagi, JPN) ,  LI Bin (Tohoku Univ., Miyagi, JPN) ,  TSUJI Kenji (Tohoku Univ., Miyagi, JPN) ,  KONDO Akiko (Tohoku Univ., Miyagi, JPN) ,  TADAKAWA Mari (Tohoku Univ., Miyagi, JPN) ,  NAGASE Satoru (Tohoku Univ., Miyagi, JPN) ,  YAEGASHI Nobuo (Tohoku Univ., Miyagi, JPN)
Material： International Journal of Clinical Oncology  (Int J Clin Oncol)
Volume： 19  Issue： 2  Page： 354-363  Publication year： Apr. 2014 
JST Material Number： L3966A  ISSN： 1341-9625  Document type： Article
Article type： 原著論文  Country of issue： Germany, Federal Republic of (DEU)  Language： ENGLISH (EN)

Thesaurus term： nude mouse ,...
Semi thesaurus term： AKT-mTOR経路 ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A0572418&from=J-GLOBAL&jstjournalNo=L3966A") }}

JST classification (1)： Basic research of antitumor(=antineoplastic)drugs  (GW16010A)

Substance index (1)： Curcumin

Reference (30)：

• Amant F, Coosemans A, Debiec-Rychter M et al (2009) Clinical management of uterine sarcomas. Lancet Oncol 10:1188–1198
• Koivisto-Korander R, Leminen A, Heikinheimo O (2007) Mifepristone as treatment of recurrent progesterone receptor-positive uterine leiomyosarcoma. Obstet Gynecol 109:512–514
• O'Cearbhaill R, Zhou Q, Iasonos A et al (2010) Treatment of advanced uterine leiomyosarcoma with aromatase inhibitors. Gynecol Oncol 116:424–429
• Quek R, Wang Q, Morgan JA et al (2011) Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors. Clin Cancer Res 17:871–879
• Ganjoo K, Jacobs C (2010) Antiangiogenesis agents in the treatment of soft tissue sarcomas. Cancer (Phila) 116:1177–1183

Terms in the title (7)： クルクミン ,  子宮平滑筋肉腫 ,  腫瘍増殖抑制 ,  Akt ,  mTOR ,  経路 ,  標的