Art
J-GLOBAL ID：201402283190539990   Reference number：14A0951860

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

複製ストレスは老化した造血幹細胞の機能低下の強力な駆動因子である
Author (16)：
FLACH Johanna

About FLACH Johanna

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
BAKKER Sietske T.

About BAKKER Sietske T.

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
MOHRIN Mary

About MOHRIN Mary

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
PIETRAS Eric M.

About PIETRAS Eric M.

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
REYNAUD Damien

About REYNAUD Damien

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
PASSEGUE Emmanuelle

About PASSEGUE Emmanuelle

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
FLACH Johanna

About FLACH Johanna

(Comprehensive Cancer Center, Ulm, DEU)

About Comprehensive Cancer Center, Ulm, DEU

, 
CONROY Pauline C.

About CONROY Pauline C.

(National Univ. Ireland Galway, Galway, IRL)

About National Univ. Ireland Galway, Galway, IRL

, 
MORRISON Ciaran G.

About MORRISON Ciaran G.

(National Univ. Ireland Galway, Galway, IRL)

About National Univ. Ireland Galway, Galway, IRL

, 
ALVAREZ Silvia

About ALVAREZ Silvia

(Spanish National Cancer Res. Centre (CNIO), Madrid, ESP)

About Spanish National Cancer Res. Centre (CNIO), Madrid, ESP

, 
MENDEZ Juan

About MENDEZ Juan

(Spanish National Cancer Res. Centre (CNIO), Madrid, ESP)

About Spanish National Cancer Res. Centre (CNIO), Madrid, ESP

, 
DIOLAITI Morgan E.

About DIOLAITI Morgan E.

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
STOHR Bradley A.

About STOHR Bradley A.

(Univ. California San Francisco, California, USA)

About Univ. California San Francisco, California, USA

, 
UGARTE Fernando

About UGARTE Fernando

(Univ. California Santa Cruz, California, USA)

About Univ. California Santa Cruz, California, USA

, 
FORSBERG E. Camilla

About FORSBERG E. Camilla

(Univ. California Santa Cruz, California, USA)

About Univ. California Santa Cruz, California, USA

, 
LE BEAU Michelle M.

About LE BEAU Michelle M.

(Univ. Chicago, Illinois, USA)

About Univ. Chicago, Illinois, USA


Material：
Nature (London)  (Nature (Lond))

About Nature (London)


Volume： 512  Issue： 7513  Page： 198-202  Publication year： Aug. 14, 2014 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)
Thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
*hematopoietic stem cell

About hematopoietic stem cell

, 
*cell aging

About cell aging

, 
DNA Replication

About DNA Replication

, 
rRNA gene

About rRNA gene

, 
stress (physiology)

About stress (physiology)

, 
nucleolus

About nucleolus

, 
histone

About histone

, 
post-translational modification

About post-translational modification

, 
DNA helicase

About DNA helicase

, 
gamma H2AX

About gamma H2AX

, 
transcription control

About transcription control

, 
*replication stress

About replication stress

, 
replicating fork

About replicating fork

, 
Gene Expression Regulation

About Gene Expression Regulation

, 
Heredity

About Heredity


Semi thesaurus term：
Thesaurus term/Semi thesaurus term
Keywords indexed to the article.
All keywords is available on JDreamIII(charged).
On J-GLOBAL, this item will be available after more than half a year after the record posted. In addtion, medical articles require to login to MyJ-GLOBAL.
genetic regulation

About genetic regulation


JST classification (2)：
JST classification
Category name(code) classified by JST.
Gene replication 
(EC02030F)

About Gene replication

,  Hematopoietic system 
(EJ07020Y)

About Hematopoietic system

Terms in the title (5)：
Terms in the title
Keywords automatically extracted from the title.
複製ストレス

About 複製ストレス

, 
老化

About 老化

, 
造血幹細胞

About 造血幹細胞

, 
機能低下

About 機能低下

, 
因子

About 因子


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