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J-GLOBAL ID:201402286461523318   Reference number:14A1044093

Suppression of the TGF-β1-induced protein expression of SNAI1 and N-cadherin by miR-199a

miR-199aによるSNAI1とN-カドヘリンのTGF-β1誘発性蛋白質発現の抑制
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Volume: 19  Issue:Page: 667-675  Publication year: Sep. 2014 
JST Material Number: W0935A  ISSN: 1356-9597  CODEN: GECEFL  Document type: Article
Article type: 原著論文  Country of issue: Australia (AUS)  Language: ENGLISH (EN)
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Gene expression  ,  Chemistry,biochemistry and pathology of tumors(=neoplasms)  ,  Basic research of antitumor(=antineoplastic)drugs 
Reference (37):
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  • Bracken, C.P., Gregory, P.A., Kolesnikoff, N., Bert, A.G., Wang, J., Shannon, M.F. & Goodall, G.J. (2008) A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res. 68, 7846-7854.
  • Cano, A., Pérez-Moreno, M.A., Rodrigo, I., Locascio, A., Blanco, M.J., del Barrio, M.G., Portillo, F. & Nieto, M.A. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat. Cell Biol. 2, 76-83.
  • Chen, R., Alvero, A.B., Silasi, D.A., Kelly, M.G., Fest, S., Visintin, I., Leiser, A., Schwartz, P.E., Rutherford, T. & Mor, G. (2008) Regulation of IKKβ by miR-199a affects NF-κB activity in ovarian cancer cells. Oncogene 27, 4712- 4723.
  • Dai, L., Gu, L. & Di, W. (2012) MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKKβ/NF-κB pathway and reduced interleukin-8 expression. Mol. Hum. Reprod. 18, 136-145.
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