Art

J-GLOBAL ID：201402289366702034   Reference number：14A1035937

Inhibition of the NF-κB pathway as a candidate therapeutic strategy for cryopyrin-associated periodic syndrome

クリオピリン関連周期熱症候群の治療戦略候補としてのNF-κB経路の阻害

Author (8)： SHIMOGAKI Satoka (Tokyo Medical and Dental Univ. Graduate School of Health Care Sci., Tokyo, JPN) ,  SHIMOGAKI Satoka (Saitama Medical Univ., Saitama, JPN) ,  ITO Sayaka (Tokyo Medical and Dental Univ. Graduate School of Health Care Sci., Tokyo, JPN) ,  KOMATSU Sachiyo (Tokyo Medical and Dental Univ. Graduate School of Health Care Sci., Tokyo, JPN) ,  KOIKE Ryuji (Tokyo Medical and Dental Univ. Graduate School of Medical and Dental Sci., Tokyo, JPN) ,  MIYASAKA Nobuyuki (Tokyo Medical and Dental Univ. Graduate School of Medical and Dental Sci., Tokyo, JPN) ,  UMEZAWA Kazuo (Aichi Medical Univ. School of Medicine, Aichi, JPN) ,  KUBOTA Tetsuo (Tokyo Medical and Dental Univ. Graduate School of Health Care Sci., Tokyo, JPN)
Material： Modern Rheumatology  (Mod Rheumatol)
Volume： 24  Issue： 3  Page： 517-524  Publication year： May. 2014 
JST Material Number： L5142A  ISSN： 1439-7595  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： human(primates) ,...
Semi thesaurus term： Muckle-Wells syndrome ,...

Register(free) or Log In to access     To see more with JDream III (charged).   {{ this.onShowAbsJLink("http://jdream3.com/lp/jglobal/index.html?docNo=14A1035937&from=J-GLOBAL&jstjournalNo=L5142A") }}

JST classification (1)： Immunologic diseases,allergic diseases in general.  (GD04010C)

Reference (33)：

• Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001;29(3):301-5.
• Feldmann J, Prieur AM, Quartier P, Berquin P, Certain S, Cortis E, et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet. 2002;71(1):198-203.
• Masters SL, Simon A, Aksentijevich I, Kastner DL. Horror autoinflammaticus: the molecular pathophysiology of autoinflammatory disease. Annu Rev Immunol. 2009;27:621-68.
• Ye Z, Ting JP. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Curr Opin Immunol. 2008;20(1):3-9.
• Franchi L, Warner N, Viani K, Nunez G. Function of Nod-like receptors in microbial recognition and host defense. Immunol Rev. 2009;227(1):106-28.

Terms in the title (4)： クリオピリン関連周期熱症候群 ,  治療戦略 ,  NF-κB経路 ,  阻害