Art

J-GLOBAL ID：201402291434257618   Reference number：14A0666791

SYNTHETIC ACCESS TO POLY-SUBSTITUTED 11H-PYRIDO[3,2-a]CARBAZOLES, A DNA-INTERCALATING ELLIPTICINE RELATED STRUCTURE, AND THEIR ANTIPROLIFERATIVE ACTIVITY

多置換11H-ピリド[3,2-a]カルバゾール類への合成アクセス,DNAインターカレーティングエリプチシン関連組織およびそれらの抗増殖作用

Author (14)： WU Ming-Yu (Okayama Univ., Okayama, JPN) ,  WU Ming-Yu (Sichuan Univ., Chengdu, CHN) ,  SHABAN Elkhabiry (Okayama Univ., Okayama, JPN) ,  SWITALSKA Marta (Inst. of Immunology and Experimental Therapy, Polish Acad. of Sci., Wroclaw, POL) ,  WANG Ning (Okayama Univ., Okayama, JPN) ,  SHIMODA Miho (Okayama Univ., Okayama, JPN) ,  MIZUTANI Yusuke (Okayama Univ. Sci., Okayama, JPN) ,  YOSHIDA Megumi (Okayama Univ., Okayama, JPN) ,  MEI Zhen-Wu (Okayama Univ., Okayama, JPN) ,  KAWAFUCHI Hiroyuki (Toyama National Coll. of Technol., Toyama, JPN) ,  NOKAMI Junzo (Okayama Univ. Sci., Okayama, JPN) ,  WIETRZYK Joanna (Inst. of Immunology and Experimental Therapy, Polish Acad. of Sci., Wroclaw, POL) ,  YU Xiao-Qi (Sichuan Univ., Chengdu, CHN) ,  INOKUCHI Tsutomu (Okayama Univ., Okayama, JPN)
Material： Heterocycles  (International Journal for Reviews and Communications in Heterocyclic Chemistry)
Volume： 89  Issue： 6  Page： 1427-1440  Publication year： Jun. 01, 2014 
JST Material Number： S0966A  ISSN： 0385-5414  CODEN： HTCYAM  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： action and effect ,  *nitrogen heterocyclic compound ,  DNA ,  enamine ,  enone ,  chemical synthesis ,  molecular structure ,  Fischer indole synthesis ,  *cyclization reaction ,  effect ,  indole alkaloid ,  polynuclear aromatic compound ,  oxidation ,  enaminone ,  Bioeffect ,  Carbazoles ,  Pyridines ,  anti-proliferative activity
Semi thesaurus term： carbazole derivative ,  Pyridines ,  anti-proliferative activity

JST classification (2)： Nitrogen heterocycles in general  (CF07040G) ,  Cyclization reaction,ring-opening reaction  (CF02050I)

Substance index (13)： Ellipticine ,  5,6-Dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  8-Bromo-5,6-dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  6-Methyl-5,6-dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  6-Phenyl-5,6-dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  11H-Pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  8-Bromo-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  6-Methyl-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  6-Phenyl-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  6,6-Dimethyl-5,6-dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  5,6-Dimethyl-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  5-Oxo-6,6-dimethyl-5,6-dihydro-11H-pyrido[3,2-a]carbazole-2-carboxylic acid methyl ester ,  4-Methyl-(11H-pyrido[3,2-a]carbazole-4-ium)-2-carboxylic acid methyl ester

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Terms in the title (5)： 置換 ,  カルバゾール類 ,  DNA ,  組織 ,  抗増殖作用