Art

J-GLOBAL ID：201402292458970516   Reference number：14A0672375

Ubiquitin is phosphorylated by PINK1 to activate parkin

PINK1によってリン酸化されたユビキチンがパーキンを活性化する

Author (21)： KOYANO Fumika (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  OKATSU Kei (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  GO Etsu (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  KIMURA Mayumi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  KIMURA Yoko (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  TSUCHIYA Hikaru (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  YOSHIHARA Hidehito (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  SAEKI Yasushi (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  TANAKA Keiji (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  MATSUDA Noriyuki (Tokyo Metropolitan Inst. of Medical Sci., Tokyo, JPN) ,  KOYANO Fumika (Univ. Tokyo, Chiba, JPN) ,  OKATSU Kei (Univ. Tokyo, Chiba, JPN) ,  KOSAKO Hidetaka (Univ. Tokushima, Tokushima, JPN) ,  TAMURA Yasushi (Nagoya Univ., Aichi, JPN) ,  KIMURA Yoko (Shizuoka Univ., Shizuoka, JPN) ,  HIROKAWA Takatsugu (National Inst. of Advanced Industrial Sci. and Technol., Tokyo, JPN) ,  ENDO Toshiya (Nagoya Univ., Aichi, JPN) ,  ENDO Toshiya (JST-CREST) ,  ENDO Toshiya (Kyoto Sangyo Univ., Kyoto, JPN) ,  FON Edward A. (McGill Univ., Quebec, CAN) ,  TREMPE Jean-Francois (McGill Univ., Quebec, CAN)
Material： Nature (London)  (Nature (Lond))
Volume： 510  Issue： 7503  Page： 162-166  Publication year： Jun. 05, 2014 
JST Material Number： D0193B  ISSN： 0028-0836  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *peptide synthase ,  phosphorylation ,  ubiquitin ,  *serine-threonine kinase ,  Mitochondria ,  substrate (biochemistry) ,  intermolecular interaction ,  Enzyme Activation ,  membrane potential ,  enzyme inhibition ,  *Parkin ,  autoinhibition ,  *PTEN-induced putative kinase 1 ,  protein-protein interaction
Semi thesaurus term： *PINK1 ,  protein interaction

JST classification (2)： Biological function  (EB03040U) ,  Enzyme physiology  (EJ02020P)

Terms in the title (5)： PINK1 ,  リン酸化 ,  ユビキチン ,  パーキン ,  活性化