Art

J-GLOBAL ID：201402296007181335   Reference number：14A0501900

Pharmacokinetic implications of augmented renal clearance (ARC) in patients with systemic inflammatory response syndrome (SIRS)/sepsis: Importance of therapeutic drug management (TDM)

SIRS患者の薬物体内動態におけるARC-Augmented Renal Clearanceの影響:TDMの重要性

Author (4)： SHIMAMOTO YUKO (国立循環器病研究セ 薬剤部) ,  FUKUDA TSUYOSHI (Univ. Cincinnati Coll. Medicine, Ohio, USA) ,  TANAKA KAZUHIKO (仁真会 白鷺病院) ,  SADAMITSU DAIKAI (大阪医療セ 救命救急セ)
Material： TDM研究  (Japanese Journal of Therapeutic Drug Monitoring)
Volume： 31  Issue： 2  Page： 57-61  Publication year： Apr. 15, 2014 
JST Material Number： L0317A  ISSN： 0911-1026  Document type： Article
Article type： 文献レビュー  Country of issue： Japan (JPN)  Language： JAPANESE (JA)

Thesaurus term： *systemic inflammatory response syndrome ,...
Semi thesaurus term： *Augmented Renal Clearance

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JST classification (3)： Immunologic diseases,allergic diseases in general.  (GD04010C) ,  Clinical application of antibacterial drugs  (GW17030D) ,  Clinical biopharmacy  (GY01022L)

Substance index (1)： Vancomycin

Reference (9)：

• Bone RC, Grodzin CJ, Balk RA. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest. 1997 ; 112 (1) : 235-243.
• Roberts JA, Lipman J. Pharmacokinetic issues for antibiotics in the critically ill patient. Crit Care Med. 2009 ; 37 (3) : 840-851.
• Baptista JP, Sousa E, Martins PJ, Pimentel JM. Augmented renal clearance in septic patients and implications for vancomycin optimisation. Int J Antimicrob Agents. 2012 ; 39 (5) : 420-423.
• Troger U, Drust A, Martens-Lobenhoffer J, Taney I, Braun-Dullaeus RC, Bode-Boger SM. Decreased meropenem levels in Intensive Care Unit patients with augmented renal clearance: benefit of therapeutic drug monitoring. Int J Antimicrob Agents. 2012 ; 40 (4) : 370-372.
• Roberts JA, Lipman J. Optimal doripenem dosing simulations in critically ill nosocomial pneumonia patients with obesity, augmented renal clearance, and decreased bacterial susceptibility. Crit Care Med. 2013 ; 41 (2) : 489-495.

Terms in the title (6)： SIRS ,  患者 ,  薬物体内動態 ,  ARC ,  TDM ,  重要性