Art

J-GLOBAL ID：201402296205013472   Reference number：14A0130919

RNF168 ubiquitylates 53BP1 and controls its response to DNA double-strand breaks

RNF168は53BP1をユビキチン化しそのDNA二本鎖切断に対する反応を制御する

Author (11)： BOHGAKI Miyuki (Univ. Toronto, ON, CAN) ,  BOHGAKI Toshiyuki (Univ. Toronto, ON, CAN) ,  EL GHAMRASNI Samah (Univ. Toronto, ON, CAN) ,  SRIKUMAR Tharan (Univ. Toronto, ON, CAN) ,  MAIRE Georges (Hospital for Sick Children, ON, CAN) ,  PANIER Stephanie (Univ. Toronto, ON, CAN) ,  FRADET-TURCOTTE Amelie (Univ. Toronto, ON, CAN) ,  STEWART Grant S. (Birmingham Univ., Birmingham, GBR) ,  RAUGHT Brian (Univ. Toronto, ON, CAN) ,  HAKEM Anne (Univ. Toronto, ON, CAN) ,  HAKEM Razqallah (Univ. Toronto, ON, CAN)
Material： Proceedings of the National Academy of Sciences of the United States of America  (PNAS)
Volume： 110  Issue： 52  Page： 20982-20987  Publication year： Dec. 24, 2013 
JST Material Number： D0387A  ISSN： 0027-8424  Document type： Article
Article type： 原著論文  Country of issue： United States (USA)  Language： ENGLISH (EN)

Thesaurus term： DNA double strand break ,  *ubiquitin-activating enzyme ,  Proteins ,  Ubiquitination ,  *DNA Repair ,  molecular genetic phenomenon ,  post-translational modification ,  amino acid residue ,  binding site ,  stability ,  HEK293 cell ,  fibroblast ,  cultured cell ,  *RNF168 ,  53BP1 ,  DNA damage response ,  genome stability ,  HEK293T cell ,  MEF cell ,  G2 Phase Cell Cycle Checkpoints ,  non-homologous end joining ,  Recombinational DNA Repair
Semi thesaurus term： G2 Phase checkpoint ,  NHEJ ,  DNA recombinational repair

JST classification (1)： Molecular genetics in general  (EC02010J)

Terms in the title (4)： RNF168 ,  53BP1 ,  ユビキチン化 ,  DNA二本鎖切断