Art

J-GLOBAL ID：201402296754271670   Reference number：14A0587179

Photocontrol of the mitotic kinesin Eg5 using a novel S-trityl-L-cysteine analogue as a photochromic inhibitor

光発色性阻害剤として新規なS-トリチル-L-システインアナログを用いた有系分裂キネシンEg5の光制御

Author (4)： ISHIKAWA Kumiko (Soka Univ., Tokyo, JPN) ,  TOHYAMA Kanako (Soka Univ., Tokyo, JPN) ,  MITSUHASHI Shinya (Hokkaido Univ., Sapporo, JPN) ,  MARUTA Shinsaku (Soka Univ., Tokyo, JPN)
Material： Journal of Biochemistry  (JB)
Volume： 155  Issue： 4  Page： 257-263  Publication year： Apr. 2014 
JST Material Number： W1920A  ISSN： 0021-924X  CODEN： JOBIAO  Document type： Article
Article type： 原著論文  Country of issue： United Kingdom (GBR)  Language： ENGLISH (EN)

Thesaurus term： *ATPase ,...
Semi thesaurus term： *kinesin Eg5

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JST classification (3)： Enzyme in general  (EB09010D) ,  Biological function  (EB03040U) ,  Cell division and proliferation  (EF02020D)

Substance index (2)： S-Trityl-L-cysteine ,  S-[2-[[4-[[4-[[2-(Tritylamino)acetyl]amino]phenyl]azo]phenyl]amino]-2-oxoethyl]-N-acetyl-L-cysteine

Reference (26)：

• Cole, D.G., Saxton, W.M., Sheehan, K.B., and Scholey, J.M. (1994) A 'slow' homotetrameric kinesin-related motor protein purified from Drosophila embryos. J. Biol. Chem. 269, 22913-22916
• Blangy, A., Lane, H.A., d'Herin, P., Harper, M., Kress, M., and Nigg, E.A. (1995) Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo. Cell 83, 1159-1169
• Schiff, P.B. and Horwitz, S.B. (1980) Taxol stabilizes microtubules in mouse fibroblast cells. Proc. Natl Acad. Sci. USA 77, 1561-1565
• Horwitz, S.B. (1994) Taxol (paclitaxel): mechanisms of action. Ann. Oncol. 5, S3-S6
• Cavaletti, G., Cavalletti, E., Montaguti, P., Oggioni, N., De Negri, O., and Tredici, G. (1997) Effect on the peripheral nervous system of the short-term intravenous administration of paclitaxel in the rat. Neurotoxicology 18, 137-145

Terms in the title (6)： 発色性 ,  阻害剤 ,  S-トリチル-L-システイン ,  アナログ ,  キネシンEg5 ,  光制御