Art

J-GLOBAL ID：201402297601525628   Reference number：14A0399027

The effect of anthraquinones in daiokanzoto on increasing the synthesis of sennoside A-metabolic enzyme derived from bifidobacteria

ビフィズス菌由来のセンノシドA代謝促進酵素の合成亢進における大黄甘草湯のアントラキノンの効果

Author (5)： TAKAYAMA Kento (Fukuyama Univ., Hiroshima, JPN) ,  MORITA Tetsuo (Fukuyama Univ., Hiroshima, JPN) ,  TABUCHI Norihiko (Fukuyama Univ., Hiroshima, JPN) ,  FUKUNAGA Masahito (Fukuyama Univ., Hiroshima, JPN) ,  OKAMURA Nobuyuki (Fukuyama Univ., Hiroshima, JPN)
Material： Journal of Traditional Medicines  (和漢医薬学雑誌)
Volume： 30  Issue： 5/6  Page： 215-220  Publication year： Mar. 10, 2014 
JST Material Number： Y0941A  ISSN： 1880-1447  Document type： Article
Article type： 原著論文  Country of issue： Japan (JPN)  Language： ENGLISH (EN)

Thesaurus term： *Chinese drug ,...
Semi thesaurus term： Bifidobacterium ,...

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JST classification (1)： Basic research of pharmacology of crude drugs  (GX06020J)

Substance index (2)： Sennoside A ,  Anthraquinone

Reference (14)：

• 1)Miyoshi, A., Masamune, O., Fukutomi, H., Mori, H., Miwa, T., Kojima, K., Aono, M., Nakajima, M.: The clinical effect of TSUMURA daiokanzoto extract granules for ethical use (TJ-84) by double blind test against the constipation. Gastroenterology, 18, 299-312, 1994.
• 2)Matsumoto, M., Ishige, A., Yuzawa, Y., Kondo, M., Muramatsu, K., Watanabe, K.: Promotion of intestinal peristalsis by bifidobacterium spp. capable of hydrolyzing sennosides in mice. PLoS ONE, 7, e31700, 2012.
• 3)Kobashi, K., Nishimura, T., Kusaka, M., Hattori, M., Namba, T.: Metabolism of sennosides by human intestinal bacteria. Planta Med., 40, 225-236, 1980.
• 4)Hattori, M., Namba, T., Akao, T., Kobashi, K.: Metabolism of sennosides by human intestinal bacteria. Pharmacology, 36, 172-179, 1988.
• 5)Ishihara, M., Homma, M., Kuno, E., Watanabe, M., Kohda, Y.: Combination use of Kampo-medicines and drugs affecting intestinal bacterial flora. YAKUGAKU ZASSHI, 122, 695-701, 2002.

Terms in the title (7)： ビフィズス菌 ,  センノシドA ,  代謝促進 ,  酵素 ,  亢進 ,  大黄甘草湯 ,  アントラキノン