J-GLOBAL ID:201410093443033093   Research Resource code:NBDC00490 Update date:Jan. 16, 2022

HATODAS: Heavy-atom Database System

HATODAS(アーカイブ): Heavy-atom Database System
Owning Organization:
Resource classification: Database
Tag (subject)  (2): Protein ,  Chemical compound
Tag (data type)  (2): Sequence ,  3D structure
This database is named HATODAS, meaning Heavy-ATOm DAtabase System. The purpose is to assist the researcher in preparing heavy-atom derivatives of a certain target protein with greater ease. It contains a list of familiar heavy atom derivatives. Whereas, conventionally, derivatives are prepared through a lengthy process of 'hit-or-miss' procedures, searching this collection of data produces a result of suggested heavy-atom reagents for the target protein, determined by its crystallization conditions and amino-acid sequence. Using this database when studying the structure-determining process of target proteins, revealed that 93 particular sequences (motifs) were more often noticed to be present at the actual heavy-atom binding sites. These sequences are therefore perceived to be preferred for successful heavy-atom binding. The site provides a link to the RIKEN Harima Heavy-atom Database.
Source: NBDC
Record maintainer: Integbio Database Catalog
Record license: Creative Commons CC0 license

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