Rchr
J-GLOBAL ID：201501004840280625
Update date: Oct. 29, 2024
Yokota Takashi
ヨコタ タカシ | Yokota Takashi
Affiliation and department：
Job title：
Senior Lecturer
Homepage URL (1)：
https://kaken.nii.ac.jp/d/r/90374321.ja.html
Research field (3)：
Biological, health, and medical informatics
, Cardiology
, Sports science
Research keywords (11)：
Preventive medicine
, Hypertension
, ICT
, Digital health
, Sports medicine
, Exercise physiology
, Heart failure
, Mitochondria
, Gut microbiota
, Diabetes
, Oxidative stress
Research theme for competitive and other funds (16)：
- 2022 - 2025 心房細動の病態進行における心臓周囲脂肪ミトコンドリア機能の役割
- 2021 - 2025 末梢血単核球ミトコンドリア機能を筋ジストロフィーの重症度評価・治療に応用する。
- 2021 - 2025 The study for prevention of cardiovascular disease by machine learning model using personal health records
- 2021 - 2024 Development of early detection method for adriamycin-induced cardiomyopathy based on the immunosenescence
- 2021 - 2024 マイオカインによる老化進展制御機構の解明
- 2018 - 2024 Role of alpha-defensins derived from the small intestine and gut microbiota in heart failure
- 2018 - 2022 Impact of myocardial fibrosis on exercise capacity in heart failure with preserved ejection fraction
- 2015 - 2022 Center of Innovation Program from the Japan Science and Technology Agency (JPMJCE1301)
- 2018 - 2021 Study on the mechanism of regulation of mitochondrial function by brain-derived neurotrophic factor
- 2017 - 2020 The role of protein lysine-acetlation in congenital heart disease
- 2018 - 2020 Study for prevention of hypertensive disease progression using self-care
- 2015 - 2018 Effects of skeletal muscle ischemic preconditioning for fatigability and damage protection
- 2015 - 2018 Role of epicardial adipose tissue mitochondria in cardiovascular disease
- 2014 - 2017 The role of mitoNEET on the regulation of mitochondrial function in skeletal muscle failure
- 2015 - 2017 Study for Development and Verification of Telemedicine for Stroke and Cardiovascular Disease
- 2011 - 2013 Resistance training with blood flow restriction: from basic physiological study to creative clinical application
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Papers (110)：
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Takeshi Sota, Yoshiharu Kinugasa, Natsuko Nakayama, Kensuke Nakamura, Masayuki Hirai, Masahiko Kato, Taisuke Ono, Masashige Takahashi, Hisashi Matsuo, Ryuichi Matsukawa, et al. Associations of serum branched-chain amino acid and marine omega-3 fatty acid levels with exercise intolerance in heart failure patients. Clinical Nutrition Open Science. 2024. 57. 241-252
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Takashi Yokota, Shintaro Kinugawa, Arata Fukushima, Takahiro Okumura, Toyoaki Murohara, Hiroyuki Tsutsui. Efficacy and safety of the urate-lowering agent febuxostat in chronic heart failure patients with hyperuricemia: results from the LEAF-CHF study. Heart and Vessels. 2024
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Haruka Handa, Yasuhito Onodera, Tsukasa Oikawa, Shingo Takada, Koji Ueda, Daiki Setoyama, Takashi Yokota, Miwako Yamasaki, Masahiko Watanabe, Yoshizuki Fumoto, et al. MitoNEET reduces the mitochondrial oxidative phosphorylation during epithelial-mesenchymal transition. Preprint. 2024
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Takashi Yokota. Skeletal muscle mitochondria: A potential target for postmenopausal hormone replacement therapy. Acta Physiologica. 2024. 240. 6. e14149
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Hiroyuki Natsui, Masaya Watanabe, Takashi Yokota, Satonori Tsuneta, Yoshizuki Fumoto, Haruka Handa, Matsushima Shouji, Jiro Koya, Kotaro Nishino, Daishiro Tatsuta, et al. Influence of epicardial adipose tissue inflammation and adipocyte size on postoperative atrial fibrillation in patients after cardiovascular surgery. Physiological Reports. 2024. 12. 6. e15957
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MISC (198)：
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山内 裕貴, 中村 昭伸, 横田 卓, 高橋 清彦, 川田 晋一朗, 土田 和久, 大森 一乃, 野本 博司, 亀田 啓, 曹 圭龍, et al. SGLT2阻害薬はミトコンドリア機能の改善を介し膵β細胞量・機能を保護する. 日本内分泌学会雑誌. 2022. 98. 1. 361-361
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Suppression of Mitochondrial Oxidative Stress and Atrial Fibrillation Inducibility by SGLT2 Inhibitors in Diabetic Rats. 2022. 84
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Takashi Yokota. Future of Heart Failure Treatment and Cardiac Rehabilitation. 2021. 1238. 40-43
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Yuki Yamauchi, Akinobu Nakamura, Takashi Yokota, Kiyohiko Takahashi, Shinichiro Kawata, Kazuhisa Tsuchida, Kazuno Omori, Hiroshi Nomoto, Hiraku Kameda, Kyuyong Cho, et al. Improved Mitochondria! Function by Luseogliflozin Prevents Pancreatic Beta-Cell Damage. DIABETES. 2021. 70
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山内 裕貴, 中村 昭伸, 横田 卓, 高橋 清彦, 川田 晋一朗, 土田 和久, 大森 一乃, 野本 博司, 亀田 啓, 曹 圭龍, et al. SGLT2阻害薬はミトコンドリア機能の改善を介し膵β細胞を保護する. 糖尿病. 2021. 64. Suppl.1. 6-6
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Patents (1)：
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Method for evaluating pathology of cardiac failure
Lectures and oral presentations (68)：
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肥満における筋内脂肪蓄積と 運動機能障害
(第43回日本臨床運動療法学会学術集会 2024)
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ゲノム情報を活用した次世代型健診: 生活習慣病・認知症
(第65回日本人間ドック・予防医療学会学術大会 2024)
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Self-care intervention using mobile application and IoT devices to reduce cardiovascular risk
(30th anniversary JACR-EAPC Joint Session 2024)
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高血圧症についてもっと知ろう!~予防に取り組む意義とその発症要因~
(オンラインセミナー 2024)
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試合開始時刻がプロ野球選手の夜間睡眠に及ぼす影響 -ウェアラブルセンサーを用いた評価-
(日本睡眠学会第45回定期学術集会 2023)
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Education (2)：
- 2005 - 2008 Hokkaido University Graduate School of Medicine PhD course
- 1992 - 1998 MD, Hokkaido University
Professional career (1)：
- PhD (Hokkaido University)
Work history (5)：
- 2019/04 - 現在 Hokkaido University Hospital Institute of Health Science Innovation for Medical Care Senior lecturer
- 2013 - 2019/03 Hokkaido University Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine Assistant Professor
- 2013/09 - 2018/08 Hokkaido University Health Care Center Assistant Professor
- 2011 - 2013 University of Copenhagen Center for Healthy Aging, Department of Biomedical Sciences Post doc
- 2009/11 - 2011 Hokkaido University, Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Assistant Professor
Awards (6)：
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