Akira Matsuo

マツオアキラ | Akira Matsuo

Affiliation and department：

Research field (3)： Experimental pathology , Respiratory medicine , Experimental pathology

Research keywords (9)：呼吸器 , lineage tracing , シングルセル、scRNA-seq , 運命転換 , 発生 , reprogramming , 癌 , Pancreas , liver

Research theme for competitive and other funds (6)：

2022 - 2026 Club細胞の運命転換と前癌病変の発生をつなぐ分子機構の解明
2022 - 2025 高解像細胞系譜解析を用いたclub細胞の恒常性維持及び疾患時の可塑性の解明
2019 - 2022 Progenitor cells and initiation of squamous metaplasia focused on club cell fate conversion
2019 - 2022 扁平上皮癌の前癌病変である扁平上皮化生の起源細胞を明らかにする
2017 - 2019 Defining the mechanism underlying transformation from adenocarcinoma to small cell lung carcinoma focused on club cell fate conversion

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Papers (14)：

Mune Sanada, Masaya Yamazaki, Tatsuya Yamada, Kosuke Fujino, Shinji Kudoh, Yuki Tenjin, Haruki Saito, Noritaka Kudo, Younosuke Sato, Akira Matsuo, et al. Heterogeneous expression and role of receptor tyrosine kinase-like orphan receptor 2 (ROR2) in small cell lung cancer. Human cell. 2023. 36. 1. 409-420
Takaaki Ito, Shinji Kudoh, Kosuke Fujino, Mune Sanada, Yuki Tenjin, Haruki Saito, Yuko Nakaishi-Fukuchi, Hiroki Kameyama, Takaya Ichimura, Naoko Udaka, et al. Pulmonary Neuroendocrine Cells and Small Cell Lung Carcinoma: Immunohistochemical Study Focusing on Mechanisms of Neuroendocrine Differentiation. Acta histochemica et cytochemica. 2022. 55. 3. 75-83
Haruki Saito, Yuki Tenjin, Tatsuya Yamada, Shinji Kudoh, Noritaka Kudo, Mune Sanada, Younosuke Sato, Akira Matsuo, Yorihisa Orita, Takaaki Ito. The role of YAP1 in small cell lung cancer. Human cell. 2022. 35. 2. 628-638
Noritaka Kudo, Shinji Kudoh, Akira Matsuo, Yamato Motooka, Takaaki Ito. ZMYM3 May Promote Cell Proliferation in Small Cell Lung Carcinoma. Acta histochemica et cytochemica. 2021. 54. 5. 143-153
Yuki Tenjin, Kumi Matsuura, Shinji Kudoh, Shingo Usuki, Tatsuya Yamada, Akira Matsuo, Younosuke Sato, Haruki Saito, Kosuke Fujino, Joeji Wakimoto, et al. Distinct transcriptional programs of SOX2 in different types of small cell lung cancers. Laboratory investigation; a journal of technical methods and pathology. 2020. 100. 12. 1575-1588

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MISC (15)：

工藤仁孝, 工藤仁孝, 松尾顕, 工藤信次, 佐藤陽之輔, 伊藤隆明, 伊藤隆明. The significance of Rb1 and Notch signaling in small cell lung carcinogenesis. 日本病理学会会誌. 2022. 111. 1. 322-322
松尾顕, 伊藤隆明. Mechanisms underlying cell fate conversion of club cells into basal cells. 日本病理学会会誌. 2021. 110. 1
工藤仁孝, 松尾顕, 工藤信次, 天神佑紀, 天神佑紀, 佐藤陽之輔, 伊藤隆明. The significance of Rb1 and Notch signaling in small cell lung carcinogenesis. 日本病理学会会誌. 2020. 109. 1. 297-297
天神佑紀, 天神佑紀, 工藤信次, 松尾顕, 佐藤陽之輔, 伊藤隆明. ASCL1-SOX2 axis in small cell lung cancer. 日本病理学会会誌. 2020. 109. 1. 297-297
Club cell dedifferentiation induced by Notch inactivation. 2019

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Patents (2)：

Lectures and oral presentations (7)：

Club細胞から基底細胞への運命転換
(日本病理学会 2021)
Club細胞から神経内分泌細胞への運命転換
(日本病理学会 2018)
Defining the mechanism of club cell plasticity in lung development, homeostasis and cancer
(2017)
肺発生及び恒常性維持におけるClub細胞の可塑性
(第3回呼吸器基礎研究を加速するための若手研究会議, 細胞・分子生物学学術部会, 第57回日本呼吸器学会学術講演会 2017)
Epiplakin1(Eppk1) is expressed in foregut endoderm, also novel marker for adult progenitor cells in injured liver
(Keystone Symposia Lung Development and Repair 2011)

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Education (1)：

Professional career (1)：

Work history (4)：

Association Membership(s) (3)：

日本発生生物学会 , 日本分子生物学会 , 日本病理学会

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