Kimura Tomonori

キムラトモノリ | Kimura Tomonori

Affiliation and department：
Other affiliations (1)：

Department of Nephrology

Homepage URL (2)： https://sites.google.com/view/chiral-medicine/%E6%97%A5%E6%9C%AC%E8%AA%9E , https://sites.google.com/view/chiral-medicine/

Research field (3)： Physiology , Cell biology , Nephrology

Research keywords (9)： Rare disease , Reverse translational research , Chiral amino acids , Precision autophagy , Metabolome , autophagy , 代謝ストレス , Chronic kidney disease , Proximal tubules

Research theme for competitive and other funds (16)：

2023 - 2027 難治性腎障害に関する調査研究
2022 - 2025 Elucidation of aging phenomenom based on the assessment of tRNA aminoacylation.
2022 - 2025 血液/尿中キラルアミノ酸の網羅的定量を基盤とする腎不全の早期低侵襲診断鑑別法開発
2022 - 2025 尿路性器癌における全身循環細菌叢及び細菌関連代謝が構築する癌局所免疫状態の解明
2022 - 2025 尿路上皮癌患者におけるD-アミノ酸発現意義の解明

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Papers (92)：

Akinaru Yamamoto, Atsunari Kawashima, Shinsuke Sakai, Masashi Mita, Nesrine Sassi, Shunsuke Inoguchi, Yuki Horibe, Akihiro Yoshimura, Masaru Tani, Liu Yutong, et al. Serum D-asparagine concentration adjusted for eGFR could serve as a novel screening tool for urothelial carcinoma. Biochemical and biophysical research communications. 2024. 733. 150701-150701
Toshimasa Morishita, Naoto Nishizaki, Sakiko Taniguchi, Shinsuke Sakai, Tomonori Kimura, Masashi Mita, Mayu Nakagawa, Amane Endo, Yoshiyuki Ohtomo, Masato Yasui, et al. Plasma D-asparagine and the D/L-serine ratio reflect chronic kidney diseases in children regardless of physique. Amino acids. 2024. 56. 1. 38-38
Tomonori Kimura, Shinsuke Sakai, Masaru Horio, Shiro Takahara, Shoto Ishigo, Maiko Nakane, Eiichi Negishi, Hiroshi Imoto, Masashi Mita, Kenji Hamase, et al. Kinetical analysis of D-alanine upon oral intake. medRxiv. 2024
Shihoko Kimura-Ohba, Mieko Kitamura, Yusuke Tsukamoto, Shigetoyo Kogaki, Shinsuke Sakai, Hiroaki Fushimi, Keiko Matsuoka, Makoto Takeuchi, Kyoko Itoh, Keiji Ueda, et al. Viral entry and translation in brain endothelia provoke influenza-associated encephalopathy. Acta neuropathologica. 2024. 147. 1. 77-77
Pattama Wiriyasermkul, Satomi Moriyama, Masataka Suzuki, Pornparn Kongpracha, Nodoka Nakamae, Saki Takeshita, Yoko Tanaka, Akina Matsuda, Masaki Miyasaka, Kenji Hamase, et al. A multi-hierarchical approach reveals d-serine as a hidden substrate of sodium-coupled monocarboxylate transporters. eLife. 2024. 12

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MISC (167)：

軸屋良介, 野口剛, 前川滋克, 小原航, 沼倉一幸, 羽渕友則, 古屋充子, 馬場理也, 三浦裕司, 木村剛, et al. 腎癌の多様性と癌の自然史の関連についての解析研究. 腎癌研究会会報. 2024. 54. 23-23
武呂幸治, 山田龍, 森西卓也, 岩重洋平, 山本恵則, 木村友則, 中西真, 柳田素子. 老化細胞系譜追跡はネフロン単位の近位尿細管老化を可視化する. 日本腎臓学会誌. 2024. 66. 4. 609-609
酒井晋介, 田中陽一, 木村志保子, 部坂篤, 浜瀬健司, 三田真史, 土居雅夫, 木村友則, 猪阪善隆. D-アラニンは既日リズムと腎糖新生に影響する. 日本腎臓学会誌. 2024. 66. 4. 610-610
潮雄介, 片岡浩史, 島田陽介, 西尾妙織, 望月俊雄, 眞部俊, 土谷健, 新田孝作, 星野純一, 木村友則, et al. 常染色体顕性多発性嚢胞腎における脳動脈瘤と脳出血の有病率と特徴. 日本腎臓学会誌. 2024. 66. 4. 628-628
森下俊真, 森下俊真, 西崎直人, 仲川真由, 遠藤周, 木村友則, 三田真史, 大友義之, 清水俊明, 安井正人, et al. D-asparagineとD-/L-serine比は体格に関係なく慢性腎臓病を反映する. 日本小児腎臓病学会雑誌(Web). 2024. 37

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Education (3)：

- 2012 Osaka University Graduate School Medicine
- 2003 Osaka University Medicine
- 1998 Tokyo University Engineering

Work history (7)：

2017 - 現在 Osaka University
2018/12 - 2023/10 National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Reverse Translational Research Project Project Leader
2017/07 - 2023/10 National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) KAGAMI Project Project Leader
2018/10 - 2023/03 National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN) Center for Rare Disease Research Director
2016 - 2017 Osaka University Graduate School of Medicine Department of Nephrology Associate Professor

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Awards (10)：

2020/10 - National Academy of Medicine, Healthy Longevity Grand Challenge Catalyst Award, Development of Diagnosis and Therapeutics for Age-related Diseases Through the Research of D-Amino Acids
2018/06 - Japanese Society of Nephrology Ohshima award
2017/01 - 19th Takeda Science Foundation Symposium on Bioscience, Poster Award, Immune regulation through TRIM-regulated precision autophagy and secretion.
2016/12 - 45th Annual Meeting of Japanese Society for Immunology Best presentation award Immune regulation through TRIM-regulated precision autophagy and secretion.
2013 - Japanese Society of Nephrology YIA Autophagy protects kidney from mitochondrial metabolic stress

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Association Membership(s) (4)：

THE JAPANESE SOCIETY FOR DIALYSIS THERAPY , JAPANESE SOCIETY OF NEPHROLOGY , THE JAPANESE SOCIETY OF INTERNAL MEDICINE , D-アミノ酸学会

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