2019 - 2022 Regulatory mechanisms of the antiepileptic ligand-receptor level to control excitation-inhibition balance in the brain
2017 - 2019 Regulatory mechanisms of synaptic transmission by an epilepsy-causative ligand-receptor complex
2016 - 2018 Optogenetic manipulation of protein palmitoylation for synapse organization
2015 - 2018 Mechanisms for AMPA-type glutamate receptor anchoring at the synapse
2014 - 2017 Identification of depalmitoylating enzymes
2013 - 2015 Studies on excitatory synaptic transmission regulated by neuronal ligand/receptor interactions
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Papers (25):
Takafumi Kawai, Hirotaka Narita, Kohtarou Konno, Sharmin Akter, Rizki Tsari Andriani, Hirohide Iwasaki, Shoji Nishikawa, Norihiko Yokoi, Yuko Fukata, Masaki Fukata, et al. Insight into the function of a unique voltage-sensor protein (TMEM266) and its short form in mouse cerebellum. The Biochemical journal. 2022. 479. 11. 1127-1145
Wirth A, Labus J, Galil DA, Schill Y, Schmidt S, Bunke T, Gorinski N, Yokoi N, Fukata M, Ponimaskin E. Palmitoylation of the small GTPase Cdc42 by DHHC5 modulates spine formation and gene transcription. Journal of Biological Chemistry. 2022
Norihiko Yokoi, Yuko Fukata, Kei Okatsu, Atsushi Yamagata, Yan Liu, Makoto Sanbo, Yuri Miyazaki, Teppei Goto, Manabu Abe, Hidetoshi Kassai, et al. 14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice. Cell Reports. 2021. 37. 11. 110107-110107
Hasegawa D, Ohnishi Y, Koyama E, Matsunaga S, Ohtani S, Nakanishi A, Shiga T, Chambers JK, Uchida K, Yokoi N, et al. Deleted in colorectal cancer (netrin-1 receptor) antibodies and limbic encephalitis in a cat with hippocampal necrosis. J Vet Intern Med. 2019. 33. 3. 1440-1445
Kanadome T, Yokoi N, Fukata Y, Fukata M. Systematic Screening of Depalmitoylating Enzymes and Evaluation of Their Activities by the Acyl-PEGyl Exchange Gel-Shift (APEGS) Assay. Methods Mol Biol. 2019. 2009. 83-98