Rchr
J-GLOBAL ID：201501008638025490   Update date: Feb. 24, 2026

Kotaki Tomohiro

コタキ トモヒロ | Kotaki Tomohiro
Affiliation and department：
Osaka University Research Institute for Microbial Diseases

About Osaka University Research Institute for Microbial Diseases


Job title： Assistant Professor
Research field  (1)： Virology
Research keywords  (2)： ワクチン ,  ウイルス学
Research theme for competitive and other funds  (10)：
  • 2025 - 2028 ロタウイルスとミトコンドリアの相互作用解明による感染治療標的の探索
  • 2024 - 2026 ウイルス感染応答におけるNEAT1 lncRNAの作動メカニズムの解明
  • 2022 - 2025 Analysis of rotavirus replication mechanism with a focus on viroplasm
  • 2022 - 2023 液-液相分離に着目したロタウイルスのviroplasm形成機構の解析
  • 2020 - 2022 Development of self-replicable flavivirus vector stably expressing foreign gene
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Papers (70)：
  • Tomohiro Kotaki, Yuki Akieda, Zelin Chen, Megumi Onishi, Sayuri Komatsu, Daisuke Motooka, Hiroko Omori, Shigeyuki Tamiya, Yuta Kanai, Shohei Minami, et al. Recovery of infectious recombinant human norovirus using zebrafish embryos. Proceedings of the National Academy of Sciences of the United States of America. 2025. 122. 49. e2526726122
  • Tomohiro Kotaki, Yuta Kanai, Megumi Onishi, Yusuke Sakai, Daisuke Motooka, Zelin Chen, Yasutaka Enoki, Sayuri Komatsu, Katsuhisa Hirai, Shohei Minami, et al. Single-round infectious rotaviruses with deletions of VP7 or VP4 genes, based on SA11 and WC3 strain backbones, and their potential use as viral vectors. PLoS pathogens. 2025. 21. 9. e1013484
  • Tomohiro Kotaki, Yuta Kanai, Kristen M Ogden, Megumi Onishi, Kattareeya Kumthip, Pattara Khamrin, Patcharaporn Boonyos, Pornkamol Phoosangwalthong, Phakapun Singchai, Tipsuda Luechakham, et al. A rotavirus VP4 or VP7 monoreassortant panel identifies genotypes that are less susceptible to neutralization by systemic antibodies induced by vaccination or natural infection. mBio. 2025. 16. 7. e0089725
  • Shohei Minami, Ryotaro Nouda, Katsuhisa Hirai, Zelin Chen, Tomohiro Kotaki, Yuta Kanai, Takeshi Kobayashi. Establishment of reverse genetics systems for Colorado tick fever virus. PLoS pathogens. 2025. 21. 2. e1012921
  • Yuta Kanai, Tomohiro Kotaki, Satoko Sakai, Toshie Ishisaka, Kayoko Matsuo, Yukino Yoshida, Katsuhisa Hirai, Shohei Minami, Takeshi Kobayashi. Rapid production of recombinant rotaviruses by overexpression of NSP2 and NSP5 genes with modified nucleotide sequences. Journal of virology. 2024. 98. 12. e0099624
ｍore...
MISC (3)：
Patents (3)：
  • ゼブラフィッシュを用いた組換えノロウイルスの作製
  • 一回感染性ロタウイルスおよびその利用
  • 一回感染性ロタウイルスおよびその利用
Lectures and oral presentations  (58)：
  • Rotavirus Replication and Pathogenesis: Insights into Inclusion Body Formation and Virus?Host Interactions
    (日米医学協力計画 第25回汎太平洋新興再興感染症(EID)会議 2025)
  • Optimization of Single-Round Infectious Rotavirus Vectors as Oral Vaccine Platforms
    (第2回ワクチン開発のための世界トップレベル研究開発拠点の形成事業 合同シンポジウム 2025)
  • ロタウイルスのVP4 およびVP7 遺伝子型が中和抗体感受性に及ぼす影響の解析 Analysis of the impact of rotavirus VP4 and VP7 genotypes on neutralizing antibody susceptibility
    (第71回日本ウイルス学会学術集会 2024)
  • Analysis of the impact of rotavirus VP4 and VP7 genotypes on neutralizing antibody susceptibility
    (第22回あわじ感染と免疫国際フォーラム 2024)
  • Vaccine development using a rotavirus reverse genetics system
    (2024年AMED SCARDA「ワクチン開発のための世界トップレベル研究開発拠点の形成事業」若手(合同)シンポジウム 2024)
ｍore...
Education (1)：
  • - 2016 Kobe University Graduate School of Medicine
Professional career (1)：
  • 博士(医学) (神戸大学)
Work history (4)：
  • 2021 - 現在 Osaka University Research Institute for Microbial Diseases
  • 2015 - 2021 Kobe University Graduate School of Health Sciences
  • 2019 - 2020 The University of Texas Medical Branch at Galveston
  • 2012 - 2015 Kobe University
Awards (1)：
  • 2026/01 - 大阪大学微生物病研究所 令和7年度 研究業績発表会 最優秀学術賞
Association Membership(s) (3)：
JAPANESE ASSOCIATION OF MEDICAL TECHNOLOGISTS ,  THE JAPANESE SOCIETY FOR VACCINOLOGY ,  THE JAPANESE SOCIETY FOR VIROLOGY
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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