Rchr
J-GLOBAL ID:201501009964587810   Update date: Sep. 26, 2024

Takase Hajime

タカセ ハジメ | Takase Hajime
Affiliation and department:
Research field  (4): Molecular biology ,  Neuropathology ,  Cognitive neuroscience ,  Neurosurgery
Research keywords  (9): Translational Research ,  産学連携 ,  認知機能障害 ,  神経炎症 ,  Neurovascular Unit ,  血液脳関門 ,  white matter injury ,  慢性硬膜下血腫 ,  subarachnoid hemorrhage
Research theme for competitive and other funds  (19):
  • 2023 - 2028 慢性硬膜下血腫:革新的分子病態概念の確立と非侵襲的治療法開発
  • 2023 - 2026 慢性硬膜下血腫の潜在性病態:疾患横断的な分子概念の証明と革新的低侵襲治療開発
  • 2022 - 2025 慢性硬膜下血腫の微小病態解析:慢性炎症と新生血管に着目した新規治療標的の創出
  • 2022 - 2023 多機関共同のリアルワールドデータ研究に対するrisk based approachを用いた臨床研究支援の実装と課題解決法の提案
  • 2022 - 2023 慢性硬膜下血腫の革新的非手術治療の開発:血腫発生増大メカニズムの概念実証
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Papers (54):
  • Hajime Takase, Gen Hamanaka, Tomonori Hoshino, Ryo Ohtomo, Shuzhen Guo, Emiri T. Mandeville, Eng H. Lo, Ken Arai. Transcriptomic Profiling Reveals Neuroinflammation in the Corpus Callosum of a Transgenic Mouse Model of Alzheimer’s Disease. Journal of Alzheimer's Disease. 2024. 97. 3. 1421-1433
  • Hajime Takase, Tatsuya Haze, Daisuke Yamamoto, Naoko Inagaki, Manabu Nitta, Murata Hidetoshi, Tetsuya Yamamoto. Network Meta-analysis of C5 Palsy after Anterior Cervical Decompression of 3-6 Levels: Comparing three Different Procedures. Spine. 2023
  • Gen Hamanaka, Iván Coto Hernández, Hajime Takase, Hidehiro Ishikawa, Fouzi Benboujja, Shintaro Kimura, Norito Fukuda, Shuzhen Guo, Josephine Lok, Eng H. Lo, et al. Myelination- and migration-associated genes are downregulated after phagocytosis in cultured oligodendrocyte precursor cells. Journal of Neurochemistry. 2023. 167. 4. 571-581
  • Wataru Shimohigoshi, Hajime Takase, Tatsuya Haze, Yusuke Kobayashi, Hiroshi Manaka, Takashi Kawasaki, Katsumi Sakata, Tetsuya Yamamoto. Renin-angiotensin-aldosterone system inhibitors as a risk factor for chronic subdural hematoma recurrence: A matter of debate. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2023. 32. 10. 107291-107291
  • Baoqiang Li, Ji Leng, Ikbal Şencan-Eğilmez, Hajime Takase, Mohammed Ali H Alfadhel, Buyin Fu, Mahnaz Shahidi, Eng H Lo, Ken Arai, Sava Sakadžić. Differential reductions in the capillary red-blood-cell flux between retina and brain under chronic global hypoperfusion. Neurophotonics. 2023. 10. 3. 035001-035001
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MISC (45):
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Education (2):
  • 2011 - 2015 横浜市立大学大学院 医学研究科 医科学専攻
  • 1998 - 2004 Hirosaki University School of Medicine Medicine
Professional career (1):
  • 博士(医学) (横浜市立大学)
Work history (6):
  • 2023/12 - 現在 Yokohama City University YCU Center for Novel and Exploratory Clinical Trials
  • 2021/04 - 2023/12 Yokohama City University School of Medicine Medical Course , Graduate School of Medicine Degree Program Assistant Professor
  • 2020/09 - 2021/03 藤沢湘南台病院 脳神経外科 部長
  • 2016/04 - 2020/08 Massachusetts General Hospital and Harvard Medical School Neuroprotection Research Lab
  • 2015/04 - 2016/04 横浜市立大学 医学部 脳神経外科 助教
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Awards (6):
  • 2022 - 日本脳循環代謝学会 エビデンス創出・基礎研究推進委員会認定研究 くも膜下出血後の認知機能障害:微小血管障害に起因する新規炎症分子機構の役割
  • 2021/03 - 第37回スパズム・シンポジウム 優秀論文賞
  • 2014 - 第29回日本脊髄外科学会 優秀演題
  • 2013 - 第28回日本脊髄外科学会 優秀演題
  • 2011 - 第41回日本脳卒中の外科学会 優秀ポスター賞
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Association Membership(s) (10):
国際脳循環代謝学会 ,  日本脳循環代謝学会 ,  THE JAPAN STROKE SOCIETY ,  THE JAPANESE SOCIETY OF SPINAL SURGERY ,  THE JAPANESE CONGRESS OF NEUROLOGICAL SURGEONS ,  THE JAPAN NEUROSURGICAL SOCIETY ,  日本頭痛学会 ,  日本認知症学会 ,  Society for Neuroscience ,  日本脳神経外傷学会
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